Current role of endomyocardial biopsy in the management of dilated cardiomyopathy and myocarditis

L. A. Wu, A. C. Lapeyre, L. T. Cooper

Research output: Contribution to journalArticle

63 Scopus citations

Abstract

Dilated cardiomyopathy is a common cause of congestive heart failure. Despite a thorough cardiovascular evaluation, a specific cause is frequently not found, and the disorder then is considered idiopathic. Endomyocardial biopsy (EMB) may yield diagnostic and prognostic information in patients with idiopathic dilated cardiomyopathy; however, the yield of useful information with this procedure among patients with heart failure is low, and the risks of occasional cardiac perforation and death further limit its use. Recent publications in the field of myocarditis and cardiomyopathy have renewed interest in the use of EMB in select patients to diagnose specific and potentially treatable myocarditides; however, the role of EMB in the work-up of patients with dilated cardiomyopathy is not well defined. In this article, we discuss the risks and utility of EMB in the management of patients with dilated cardiomyopathy and specific myocarditides.

Original languageEnglish (US)
Pages (from-to)1030-1038
Number of pages9
JournalMayo Clinic proceedings
Volume76
Issue number10
DOIs
StatePublished - Jan 1 2001

Keywords

  • AIDS = acquired immunodeficiency syndrome
  • DCM = dilated cardiomyopathy
  • ECG = electrocardiography
  • EMB = endomyocardial biopsy
  • GCM = giant cell myocarditis
  • HIV = human immunodeficiency virus
  • HSM = hypersensitivity myocarditis

ASJC Scopus subject areas

  • Medicine(all)

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