Current histological diagnosis of lymphomatoid granulomatosis.

Thomas V. Colby

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

The current histological criteria for the diagnosis of lymphomatoid granulomatosis (LYG) are reviewed and summarized. The majority of patients present with multiple bilateral nodules involving the lung. Key histologic features necessary for the diagnosis include a mixed mononuclear cell infiltrate that shows vascular infiltration, appreciable numbers of T-cells, and variable numbers of CD20-positive B cells that show positivity for EBER by in situ hybridization.

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Lymphomatoid Granulomatosis
In Situ Hybridization
Blood Vessels
B-Lymphocytes
Cell Count
T-Lymphocytes
Lung

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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title = "Current histological diagnosis of lymphomatoid granulomatosis.",
abstract = "The current histological criteria for the diagnosis of lymphomatoid granulomatosis (LYG) are reviewed and summarized. The majority of patients present with multiple bilateral nodules involving the lung. Key histologic features necessary for the diagnosis include a mixed mononuclear cell infiltrate that shows vascular infiltration, appreciable numbers of T-cells, and variable numbers of CD20-positive B cells that show positivity for EBER by in situ hybridization.",
author = "Colby, {Thomas V.}",
year = "2012",
month = "1",
doi = "10.1038/modpathol.2011.149",
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