Current epidemiology of mild cognitive impairment and other predementia syndromes

Francesco Panza, Alessia D'Introno, Anna Maria Colacicco, Cristiano Capurso, Angela Del Parigi, Richard John Caselli, Alberto Pilotto, Giovanni Argentieri, Pier Luigi Scapicchio, Emanuele Scafato, Antonio Capurso, Vincenzo Solfrizzi

Research output: Contribution to journalArticle

179 Citations (Scopus)

Abstract

A variety of clinically-defined predementia syndromes, with differing diagnostic criteria and nomenclature, have been proposed to describe nondisabling symptomatic cognitive deficits arising in elderly persons. Incidence and prevalence of different predementia syndromes vary as a result of different diagnostic criteria, sampling, and assessment procedures. The incidence rates of all predementia syndromes increase with age and are higher in subjects with less education; but age, educational background, and gender are not consistently related to prevalence rates. There is particular interest in "Mild Cognitive Impairment (MCI)" because this predementia syndrome is thought to be a prodromal phase of Alzheimer disease (AD). Several studies have suggested that most patients who meet MCI criteria will progress to AD, but rates of conversion to AD and dementia vary widely among studies. Furthermore, MCI definition is less consistent in population-based studies than clinical studies, in which progression to AD is also more consistent. To clarify the sources of discrepant findings in the literature, this review summarizes existing epidemiological studies of the defined clinical predementia syndromes and their progression to dementia.

Original languageEnglish (US)
Pages (from-to)633-644
Number of pages12
JournalAmerican Journal of Geriatric Psychiatry
Volume13
Issue number8
DOIs
StatePublished - 2005

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Alzheimer Disease
Epidemiology
Incidence
Terminology
Dementia
Epidemiologic Studies
Cognitive Dysfunction
Education
Population

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Geriatrics and Gerontology

Cite this

Current epidemiology of mild cognitive impairment and other predementia syndromes. / Panza, Francesco; D'Introno, Alessia; Colacicco, Anna Maria; Capurso, Cristiano; Del Parigi, Angela; Caselli, Richard John; Pilotto, Alberto; Argentieri, Giovanni; Scapicchio, Pier Luigi; Scafato, Emanuele; Capurso, Antonio; Solfrizzi, Vincenzo.

In: American Journal of Geriatric Psychiatry, Vol. 13, No. 8, 2005, p. 633-644.

Research output: Contribution to journalArticle

Panza, F, D'Introno, A, Colacicco, AM, Capurso, C, Del Parigi, A, Caselli, RJ, Pilotto, A, Argentieri, G, Scapicchio, PL, Scafato, E, Capurso, A & Solfrizzi, V 2005, 'Current epidemiology of mild cognitive impairment and other predementia syndromes', American Journal of Geriatric Psychiatry, vol. 13, no. 8, pp. 633-644. https://doi.org/10.1097/00019442-200508000-00002
Panza, Francesco ; D'Introno, Alessia ; Colacicco, Anna Maria ; Capurso, Cristiano ; Del Parigi, Angela ; Caselli, Richard John ; Pilotto, Alberto ; Argentieri, Giovanni ; Scapicchio, Pier Luigi ; Scafato, Emanuele ; Capurso, Antonio ; Solfrizzi, Vincenzo. / Current epidemiology of mild cognitive impairment and other predementia syndromes. In: American Journal of Geriatric Psychiatry. 2005 ; Vol. 13, No. 8. pp. 633-644.
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