Current concepts of the role of abdominal compartment syndrome in acute pancreatitis - An opportunity or merely an epiphenomenon

Guru Trikudanathan, Santhi Swaroop Vege

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The association of acute pancreatitis (AP) with intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) has only recently been recognized. The detrimental effects of raised intra-abdominal pressure in cardiovascular, pulmonary and renal systems have been well established. Although IAH was associated with a higher APACHE II score and multi-organ dysfunction syndrome (MODS) in severe acute pancreatitis, a causal relationship between ACS and MODS in SAP is yet to be established. It is therefore debatable whether IAH is a phenomenon causative of organ failure or an epiphenomenon seen in conjunction with other organ dysfunction. This review systemically examines the pathophysiological basis and clinical relevance of ACS in AP and summarizes all the available evidence in its management.

Original languageEnglish (US)
Pages (from-to)238-243
Number of pages6
JournalPancreatology
Volume14
Issue number4
DOIs
StatePublished - 2014

Fingerprint

Intra-Abdominal Hypertension
Pancreatitis
Organ Dysfunction Scores
APACHE
Kidney
Pressure
Lung

Keywords

  • Abdominal compartment syndrome
  • Acute pancreatitis
  • Decompressive laparotomy
  • Intra-abdominal hypertension
  • Intra-abdominal pressure
  • Severe acute pancreatitis

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Medicine(all)

Cite this

Current concepts of the role of abdominal compartment syndrome in acute pancreatitis - An opportunity or merely an epiphenomenon. / Trikudanathan, Guru; Vege, Santhi Swaroop.

In: Pancreatology, Vol. 14, No. 4, 2014, p. 238-243.

Research output: Contribution to journalArticle

@article{f648684825ae45eba0a00809a7f86dd0,
title = "Current concepts of the role of abdominal compartment syndrome in acute pancreatitis - An opportunity or merely an epiphenomenon",
abstract = "The association of acute pancreatitis (AP) with intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) has only recently been recognized. The detrimental effects of raised intra-abdominal pressure in cardiovascular, pulmonary and renal systems have been well established. Although IAH was associated with a higher APACHE II score and multi-organ dysfunction syndrome (MODS) in severe acute pancreatitis, a causal relationship between ACS and MODS in SAP is yet to be established. It is therefore debatable whether IAH is a phenomenon causative of organ failure or an epiphenomenon seen in conjunction with other organ dysfunction. This review systemically examines the pathophysiological basis and clinical relevance of ACS in AP and summarizes all the available evidence in its management.",
keywords = "Abdominal compartment syndrome, Acute pancreatitis, Decompressive laparotomy, Intra-abdominal hypertension, Intra-abdominal pressure, Severe acute pancreatitis",
author = "Guru Trikudanathan and Vege, {Santhi Swaroop}",
year = "2014",
doi = "10.1016/j.pan.2014.06.002",
language = "English (US)",
volume = "14",
pages = "238--243",
journal = "Pancreatology",
issn = "1424-3903",
publisher = "S. Karger AG",
number = "4",

}

TY - JOUR

T1 - Current concepts of the role of abdominal compartment syndrome in acute pancreatitis - An opportunity or merely an epiphenomenon

AU - Trikudanathan, Guru

AU - Vege, Santhi Swaroop

PY - 2014

Y1 - 2014

N2 - The association of acute pancreatitis (AP) with intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) has only recently been recognized. The detrimental effects of raised intra-abdominal pressure in cardiovascular, pulmonary and renal systems have been well established. Although IAH was associated with a higher APACHE II score and multi-organ dysfunction syndrome (MODS) in severe acute pancreatitis, a causal relationship between ACS and MODS in SAP is yet to be established. It is therefore debatable whether IAH is a phenomenon causative of organ failure or an epiphenomenon seen in conjunction with other organ dysfunction. This review systemically examines the pathophysiological basis and clinical relevance of ACS in AP and summarizes all the available evidence in its management.

AB - The association of acute pancreatitis (AP) with intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) has only recently been recognized. The detrimental effects of raised intra-abdominal pressure in cardiovascular, pulmonary and renal systems have been well established. Although IAH was associated with a higher APACHE II score and multi-organ dysfunction syndrome (MODS) in severe acute pancreatitis, a causal relationship between ACS and MODS in SAP is yet to be established. It is therefore debatable whether IAH is a phenomenon causative of organ failure or an epiphenomenon seen in conjunction with other organ dysfunction. This review systemically examines the pathophysiological basis and clinical relevance of ACS in AP and summarizes all the available evidence in its management.

KW - Abdominal compartment syndrome

KW - Acute pancreatitis

KW - Decompressive laparotomy

KW - Intra-abdominal hypertension

KW - Intra-abdominal pressure

KW - Severe acute pancreatitis

UR - http://www.scopus.com/inward/record.url?scp=84905084171&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84905084171&partnerID=8YFLogxK

U2 - 10.1016/j.pan.2014.06.002

DO - 10.1016/j.pan.2014.06.002

M3 - Article

VL - 14

SP - 238

EP - 243

JO - Pancreatology

JF - Pancreatology

SN - 1424-3903

IS - 4

ER -