Current challenges and opportunities for research on borderline ovarian tumors

Mark E. Sherman, Jules Berman, Michael J. Birrer, Kathleen R. Cho, Lora Hedrick Ellenson, Fred Gorstein, Jeffrey D. Seidman

Research output: Contribution to journalArticle

36 Scopus citations

Abstract

This article summarizes key issues for future research on borderline ovarian tumors that emerged at a National Cancer Institute-sponsored Borderline Ovarian Tumor Workshop held in August 2003 in Bethesda, MD. Limitations in existing research and opportunities for future advances have been highlighted. The application of new molecular techniques in combination with improved study designs holds promise for elucidating the pathogenesis of these tumors and revealing the source of the extra-ovarian lesions ("implants") with which they are frequently associated. Clarification of the etiology of borderline tumors and the pathogenesis of their associated implants is critical for improving pathological diagnosis, revising the classification system of ovarian neoplasms, and developing optimal, evidence-based clinical management algorithms.

Original languageEnglish (US)
Pages (from-to)961-970
Number of pages10
JournalHuman Pathology
Volume35
Issue number8
DOIs
StatePublished - Aug 1 2004

Keywords

  • BOT
  • M-BOT
  • S-BOT
  • SEER
  • Surveillance, Epidemiology and End Results
  • borderline
  • borderline ovarian tumor
  • epidemiology
  • low malignant potential
  • mucinous borderline ovarian tumor
  • neoplasm
  • ovary
  • pathology
  • serous borderline ovarian tumor

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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  • Cite this

    Sherman, M. E., Berman, J., Birrer, M. J., Cho, K. R., Ellenson, L. H., Gorstein, F., & Seidman, J. D. (2004). Current challenges and opportunities for research on borderline ovarian tumors. Human Pathology, 35(8), 961-970. https://doi.org/10.1016/j.humpath.2004.03.007