Cumulative Burden of Colorectal Cancer–Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer

Alexi N. Archambault, Yu Ru Su, Jihyoun Jeon, Minta Thomas, Yi Lin, David V. Conti, Aung Ko Win, Lori C. Sakoda, Iris Lansdorp-Vogelaar, Elisabeth F.P. Peterse, Ann G. Zauber, David Duggan, Andreana N. Holowatyj, Jeroen R. Huyghe, Hermann Brenner, Michelle Cotterchio, Stéphane Bézieau, Stephanie L. Schmit, Christopher K. Edlund, Melissa C. SoutheyRobert J. MacInnis, Peter T. Campbell, Jenny Chang-Claude, Martha L. Slattery, Andrew T. Chan, Amit D. Joshi, Mingyang Song, Yin Cao, Michael O. Woods, Emily White, Stephanie J. Weinstein, Cornelia M. Ulrich, Michael Hoffmeister, Stephanie A. Bien, Tabitha A. Harrison, Jochen Hampe, Christopher I. Li, Clemens Schafmayer, Kenneth Offit, Paul D. Pharoah, Victor Moreno, Annika Lindblom, Alicja Wolk, Anna H. Wu, Li Li, Marc J. Gunter, Andrea Gsur, Temitope O. Keku, Rachel Pearlman, D. Timothy Bishop, Sergi Castellví-Bel, Leticia Moreira, Pavel Vodicka, Ellen Kampman, Graham G. Giles, Demetrius Albanes, John A. Baron, Sonja I. Berndt, Stefanie Brezina, Stephan Buch, Daniel D. Buchanan, Antonia Trichopoulou, Gianluca Severi, María Dolores Chirlaque, Maria José Sánchez, Domenico Palli, Tilman Kühn, Neil Murphy, Amanda J. Cross, Andrea N. Burnett-Hartman, Stephen J. Chanock, Albert de la Chapelle, Douglas F. Easton, Faye Elliott, Dallas R. English, Edith J.M. Feskens, Liesel M. FitzGerald, Phyllis J. Goodman, John L. Hopper, Thomas J. Hudson, David J. Hunter, Eric J. Jacobs, Corinne E. Joshu, Sébastien Küry, Sanford D. Markowitz, Roger L. Milne, Elizabeth A. Platz, Gad Rennert, Hedy S. Rennert, Fredrick R. Schumacher, Robert S. Sandler, Daniela Seminara, Catherine M. Tangen, Stephen N. Thibodeau, Amanda E. Toland, Franzel J.B. van Duijnhoven, Kala Visvanathan, Ludmila Vodickova, John D. Potter, Satu Männistö, Korbinian Weigl, Jane Figueiredo, Vicente Martín, Susanna C. Larsson, Patrick S. Parfrey, Wen Yi Huang, Heinz Josef Lenz, Jose E. Castelao, Manuela Gago-Dominguez, Victor Muñoz-Garzón, Christoph Mancao, Christopher A. Haiman, Lynne R. Wilkens, Erin Siegel, Elizabeth Barry, Ban Younghusband, Bethany Van Guelpen, Sophia Harlid, Anne Zeleniuch-Jacquotte, Peter S. Liang, Mengmeng Du, Graham Casey, Noralane M. Lindor, Loic Le Marchand, Steven J. Gallinger, Mark A. Jenkins, Polly A. Newcomb, Stephen B. Gruber, Robert E. Schoen, Heather Hampel, Douglas A. Corley, Li Hsu, Ulrike Peters, Richard B. Hayes

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Cumulative Burden of Colorectal Cancer–Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer

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