CT enterography and fistulizing Crohn's disease: Clinical benefit and radiographic findings

Fargol Booya, Salma Akram, Joel Garland Fletcher, J. E. Huprich, C. Daniel Johnson, J. L. Fidler, J. M. Barlow, C. A. Solem, W. J. Sandborn, Edward Vincent Loftus, Jr

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

Background: To estimate the clinical benefit of CT enterography (CTE) in patients with fistulizing Crohn's disease and describe the appearance of fistulas at CTE. Methods: Crohn's patients who had undergone CTE, which diagnosed an abscess or fistula, were identified. A gastroenterologist reviewed clinical notes prior to and following CTE to assess the pre-CTE clinical suspicion for fistula/abscess, and post-CTE alteration in patient management. A radiologist reassessed all fistula-positive cases, which were confirmed by a non-CT reference standard, to describe their radiologic appearance. Results: Fifty-six patients had CT exams identifying 19 abscesses and 56 fistulas. There was no or remote suspicion of fistula or abscess at pre-imaging clinical assessment in 50% of patients. Thirty-four patients (61%) required a change in or initiation of medical therapy and another 10 (18%) underwent an interventional procedure based on CT enterography findings. Among 37 fistulas with reference standard confirmation, 30 (81%) were extraenteric tracts, and 32 (86%) were hyperenhancing compared to adjacent bowel loops. Most fistulas (68%) contained no internal air or fluid. Conclusion: CTE detects clinically occult fistulas and abscesses, resulting in changes in medical management and radiologic or surgical intervention. Most fistulas appear as hyperenhancing, extraenteric tracts, usually without internal air or fluid.

Original languageEnglish (US)
Pages (from-to)467-475
Number of pages9
JournalAbdominal Imaging
Volume34
Issue number4
DOIs
StatePublished - Jul 2009

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Crohn Disease
Fistula
Abscess
Air

Keywords

  • Abscesses
  • Crohn's disease
  • CT
  • Enterography
  • Fistula

ASJC Scopus subject areas

  • Gastroenterology
  • Urology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

CT enterography and fistulizing Crohn's disease : Clinical benefit and radiographic findings. / Booya, Fargol; Akram, Salma; Fletcher, Joel Garland; Huprich, J. E.; Johnson, C. Daniel; Fidler, J. L.; Barlow, J. M.; Solem, C. A.; Sandborn, W. J.; Loftus, Jr, Edward Vincent.

In: Abdominal Imaging, Vol. 34, No. 4, 07.2009, p. 467-475.

Research output: Contribution to journalArticle

Booya, Fargol ; Akram, Salma ; Fletcher, Joel Garland ; Huprich, J. E. ; Johnson, C. Daniel ; Fidler, J. L. ; Barlow, J. M. ; Solem, C. A. ; Sandborn, W. J. ; Loftus, Jr, Edward Vincent. / CT enterography and fistulizing Crohn's disease : Clinical benefit and radiographic findings. In: Abdominal Imaging. 2009 ; Vol. 34, No. 4. pp. 467-475.
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