TY - JOUR
T1 - CT-definable subtypes of chronic obstructive pulmonary disease
T2 - A statement of the fleischner society1
AU - Lynch, David A.
AU - Austin, John H.M.
AU - Hogg, James C.
AU - Grenier, Philippe A.
AU - Kauczor, Hans Ulrich
AU - Bankier, Alexander A.
AU - Barr, R. Graham
AU - Colby, Thomas V.
AU - Galvin, Jeffrey R.
AU - Gevenois, Pierre Alain
AU - Coxson, Harvey O.
AU - Hoffman, Eric A.
AU - Newell, John D.
AU - Pistolesi, Massimo
AU - Silverman, Edwin K.
AU - Crapo, James D.
N1 - Publisher Copyright:
© RSNA, 2015.
PY - 2015/10/1
Y1 - 2015/10/1
N2 - The purpose of this statement is to describe and define the phenotypic abnormalities that can be identified on visual and quantitative evaluation of computed tomographic (CT) images in subjects with chronic obstructive pulmonary disease (COPD), with the goal of contributing to a personalized approach to the treatment of patients with COPD. Quantitative CT is useful for identifying and sequentially evaluating the extent of emphysematous lung destruction, changes in airway walls, and expiratory air trapping. However, visual assessment of CT scans remains important to describe patterns of altered lung structure in COPD. The classification system proposed and illustrated in this article provides a structured approach to visual and quantitative assessment of COPD. Emphysema is classified as centrilobular (subclassified as trace, mild, moderate, confluent, and advanced destructive emphysema), panlobular, and paraseptal (subclassified as mild or substantial). Additional important visual features include airway wall thickening, inflammatory small airways disease, tracheal abnormalities, interstitial lung abnormalities, pulmonary arterial enlargement, and bronchiectasis.
AB - The purpose of this statement is to describe and define the phenotypic abnormalities that can be identified on visual and quantitative evaluation of computed tomographic (CT) images in subjects with chronic obstructive pulmonary disease (COPD), with the goal of contributing to a personalized approach to the treatment of patients with COPD. Quantitative CT is useful for identifying and sequentially evaluating the extent of emphysematous lung destruction, changes in airway walls, and expiratory air trapping. However, visual assessment of CT scans remains important to describe patterns of altered lung structure in COPD. The classification system proposed and illustrated in this article provides a structured approach to visual and quantitative assessment of COPD. Emphysema is classified as centrilobular (subclassified as trace, mild, moderate, confluent, and advanced destructive emphysema), panlobular, and paraseptal (subclassified as mild or substantial). Additional important visual features include airway wall thickening, inflammatory small airways disease, tracheal abnormalities, interstitial lung abnormalities, pulmonary arterial enlargement, and bronchiectasis.
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U2 - 10.1148/radiol.2015141579
DO - 10.1148/radiol.2015141579
M3 - Article
C2 - 25961632
AN - SCOPUS:84938118974
SN - 0033-8419
VL - 277
SP - 192
EP - 205
JO - Radiology
JF - Radiology
IS - 1
ER -