CT colonography with computer-aided detection: Automated recognition of ileocecal valve to reduce number of false-positive detections

Ronald M. Summers, Jianhua Yao, C. Daniel Johnson

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

The ileocecal valve (ICV) is a common cause of false-positive detections of polyps at computed tomographic (CT) colonography with computer-aided detection (CAD). The authors developed a CAD algorithm for differentiating the ICV from a true polyp and evaluated this algorithm by using two colonoscopy-confirmed CT colonography data sets. Data sets 1 and 2 consisted of the data obtained at CT colonographic examinations performed in 20 and 40 patients, respectively. Forty of these patients had at least one polyp 1 cm or larger. For data set 1, the proposed ICV recognition algorithm eliminated three of nine (33%; 95% confidence interval [CI]: 8%, 70%) false-positive CAD detections that were attributable to the ICV and none of the true-positive polyp detections. For data set 2, with use of identical parameters, the algorithm eliminated 11 of 18 (61%; 95% CI: 36%, 83%) false-positive detections that were attributable to the ICV and none of the true-positive detections. The thresholds used to recognize the ICV were a mean internal CT attenuation of less than - 124 HU and a volume of greater than 1.5 cm3. The proposed algorithm successfully recognized the ICV and eliminated it in some cases. This result is clinically important because, by reducing the frequency of a common cause of false-positive detections, this algorithm may improve the efficiency of physicians who use CAD.

Original languageEnglish (US)
Pages (from-to)266-272
Number of pages7
JournalRadiology
Volume233
Issue number1
DOIs
StatePublished - Oct 2004

Keywords

  • Colon neoplasms
  • Colon neoplasms, CT
  • Colon, CT
  • Computers, diagnostic aid

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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