Ct and mr of neurofibromatosis of the bladder

Keith M. Shonnard, James S. Jelinek, Richard A. Benedikt, Mark J. Kransdorf

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Neurofibromatosis of the genitourinary system is rare. We present the CT and MR findings of neurofibromas of the bladder in three patients with von Recklinghausen disease (neurofibromatosis, Type 1). In one case, genitourinary involvement was the primary presentation of the disease. Both CT and MR imaging revealed diffuse and nodular bladder wall involvement, along with pelvic sidewall and adjacent soft tissue abnormalities. The CT attenuation coefficients measured near soft tissue density. On Tl-weighted spin echo MR images the tumors revealed signal intensity slightly greater than that of skeletal muscle. Neurofibromas showed markedly increased signal intensity on Tl-weighted images relative to the surrounding soft tissues, with marked enhancement in two cases imaged following Gd-DTPA administration. Obstructive hydronephrosis was present in all cases, presumably due to neurofibromas involving the trigonal region. Pelvic sidewall tumors were visualized as rounded, nodular masses extending into the obturator foramina. In the evaluation of patients with von Recklinghausen disease, MR imaging, compared with CT, more clearly defined tumor extent within the bladder, pelvic side-walls, and surrounding soft tissues.

Original languageEnglish (US)
Pages (from-to)433-438
Number of pages6
JournalJournal of computer assisted tomography
Issue number3
StatePublished - 1992


  • Neoplasms-Computed tomography-Magnetic resonance imaging
  • Neurofibromatosis-Bladder

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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