Cryogenic micro-CT imaging of tissues

Steven M. Jorgensen, Russell T. Turner, Erik L. Ritman

Research output: Contribution to journalConference article

1 Scopus citations


In order to facilitate the full use of histological methods following micro-CT imaging a cryogenic micro-CT scanning method is presented. The method involves rapid removal of the rodent organ (or biopsy from a large animal) and cooling it down rapidly. Next, the specimen is placed inside a specially-designed vessel and maintained at liquid N2 temperature. This vessel consists of a double-walled copper container with a vacuum space between the walls which is evacuated. Beryllium 'windows' in the vessel walls minimize x-ray attenuation of the low energy x-ray photons. The specimen is mounted on a stainless steel rod so that the specimen can be rotated in the small angular steps required in the CT scanning process.

Original languageEnglish (US)
Pages (from-to)S-39
JournalAnnals of Biomedical Engineering
Issue numberSUPPL. 1
StatePublished - Dec 1 2000
Event2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA
Duration: Oct 12 2000Oct 14 2000

ASJC Scopus subject areas

  • Biomedical Engineering

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    Jorgensen, S. M., Turner, R. T., & Ritman, E. L. (2000). Cryogenic micro-CT imaging of tissues. Annals of Biomedical Engineering, 28(SUPPL. 1), S-39.