Cryoablation of recurrent sacrococcygeal tumors

Anil Nicholas Kurup, David A Woodrum, Jonathan M. Morris, Thomas D. Atwell, Grant D. Schmit, Timothy J. Welch, Michael J Yaszemski, Matthew R Callstrom

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Purpose: To review the safety and efficacy of cryoablation of recurrent sacrococcygeal tumors. Materials and Methods: The radiology departmental ablation database was retrospectively searched for cases of cryoablation performed to treat recurrences of sacrococcygeal tumors between January 1, 2010, and August 1, 2011. Patient demographics, procedure technical parameters, and patient outcomes were reviewed. Results: Five cases of recurrent chordoma and one recurrent myxopapillary ependymoma were treated with cryoablation in six patients whose ages ranged from 31 to 80 years. The tumors measured 14-39 mm in maximal dimension. Cryoablation was performed with the use of computed tomography guidance (n = 5) or a combination of ultrasound and magnetic resonance imaging guidance (n = 1). Sterile fluid was instilled to displace adjacent bowel and/or vagina in four cases, and electromyography monitoring was performed in two cases with adjacent nerve roots. Two patients with recurrent chordoma were treated for palliation of pain, with complete pain relief in one patient (pain recurred after 6 wk) and immediate reduction in pain from a score of six to a score of two on a 10-point scale in the other (pain recurred after 7 mo). Four tumors were treated for local control, with no evidence of recurrence on follow-up imaging at 3, 6, 12, and 15 months. No serious complication occurred. Conclusions: Limited results suggest cryoablation to be a safe and relatively effective means of treating recurrent sacrococcygeal neoplasms for local control or palliation of pain in this small series with short-term follow-up.

Original languageEnglish (US)
Pages (from-to)1070-1075
Number of pages6
JournalJournal of Vascular and Interventional Radiology
Volume23
Issue number8
DOIs
StatePublished - Aug 2012

Fingerprint

Cryosurgery
Pain
Chordoma
Neoplasms
Recurrence
Ependymoma
Electromyography
Vagina
Radiology
Tomography
Magnetic Resonance Imaging
Demography
Databases
Safety

Keywords

  • radiation therapy
  • RT

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Cryoablation of recurrent sacrococcygeal tumors. / Kurup, Anil Nicholas; Woodrum, David A; Morris, Jonathan M.; Atwell, Thomas D.; Schmit, Grant D.; Welch, Timothy J.; Yaszemski, Michael J; Callstrom, Matthew R.

In: Journal of Vascular and Interventional Radiology, Vol. 23, No. 8, 08.2012, p. 1070-1075.

Research output: Contribution to journalArticle

Kurup, Anil Nicholas ; Woodrum, David A ; Morris, Jonathan M. ; Atwell, Thomas D. ; Schmit, Grant D. ; Welch, Timothy J. ; Yaszemski, Michael J ; Callstrom, Matthew R. / Cryoablation of recurrent sacrococcygeal tumors. In: Journal of Vascular and Interventional Radiology. 2012 ; Vol. 23, No. 8. pp. 1070-1075.
@article{e125e9d3f58f45d2847ac2819439a6a0,
title = "Cryoablation of recurrent sacrococcygeal tumors",
abstract = "Purpose: To review the safety and efficacy of cryoablation of recurrent sacrococcygeal tumors. Materials and Methods: The radiology departmental ablation database was retrospectively searched for cases of cryoablation performed to treat recurrences of sacrococcygeal tumors between January 1, 2010, and August 1, 2011. Patient demographics, procedure technical parameters, and patient outcomes were reviewed. Results: Five cases of recurrent chordoma and one recurrent myxopapillary ependymoma were treated with cryoablation in six patients whose ages ranged from 31 to 80 years. The tumors measured 14-39 mm in maximal dimension. Cryoablation was performed with the use of computed tomography guidance (n = 5) or a combination of ultrasound and magnetic resonance imaging guidance (n = 1). Sterile fluid was instilled to displace adjacent bowel and/or vagina in four cases, and electromyography monitoring was performed in two cases with adjacent nerve roots. Two patients with recurrent chordoma were treated for palliation of pain, with complete pain relief in one patient (pain recurred after 6 wk) and immediate reduction in pain from a score of six to a score of two on a 10-point scale in the other (pain recurred after 7 mo). Four tumors were treated for local control, with no evidence of recurrence on follow-up imaging at 3, 6, 12, and 15 months. No serious complication occurred. Conclusions: Limited results suggest cryoablation to be a safe and relatively effective means of treating recurrent sacrococcygeal neoplasms for local control or palliation of pain in this small series with short-term follow-up.",
keywords = "radiation therapy, RT",
author = "Kurup, {Anil Nicholas} and Woodrum, {David A} and Morris, {Jonathan M.} and Atwell, {Thomas D.} and Schmit, {Grant D.} and Welch, {Timothy J.} and Yaszemski, {Michael J} and Callstrom, {Matthew R}",
year = "2012",
month = "8",
doi = "10.1016/j.jvir.2012.05.043",
language = "English (US)",
volume = "23",
pages = "1070--1075",
journal = "Journal of Vascular and Interventional Radiology",
issn = "1051-0443",
publisher = "Elsevier Inc.",
number = "8",

}

TY - JOUR

T1 - Cryoablation of recurrent sacrococcygeal tumors

AU - Kurup, Anil Nicholas

AU - Woodrum, David A

AU - Morris, Jonathan M.

AU - Atwell, Thomas D.

AU - Schmit, Grant D.

AU - Welch, Timothy J.

AU - Yaszemski, Michael J

AU - Callstrom, Matthew R

PY - 2012/8

Y1 - 2012/8

N2 - Purpose: To review the safety and efficacy of cryoablation of recurrent sacrococcygeal tumors. Materials and Methods: The radiology departmental ablation database was retrospectively searched for cases of cryoablation performed to treat recurrences of sacrococcygeal tumors between January 1, 2010, and August 1, 2011. Patient demographics, procedure technical parameters, and patient outcomes were reviewed. Results: Five cases of recurrent chordoma and one recurrent myxopapillary ependymoma were treated with cryoablation in six patients whose ages ranged from 31 to 80 years. The tumors measured 14-39 mm in maximal dimension. Cryoablation was performed with the use of computed tomography guidance (n = 5) or a combination of ultrasound and magnetic resonance imaging guidance (n = 1). Sterile fluid was instilled to displace adjacent bowel and/or vagina in four cases, and electromyography monitoring was performed in two cases with adjacent nerve roots. Two patients with recurrent chordoma were treated for palliation of pain, with complete pain relief in one patient (pain recurred after 6 wk) and immediate reduction in pain from a score of six to a score of two on a 10-point scale in the other (pain recurred after 7 mo). Four tumors were treated for local control, with no evidence of recurrence on follow-up imaging at 3, 6, 12, and 15 months. No serious complication occurred. Conclusions: Limited results suggest cryoablation to be a safe and relatively effective means of treating recurrent sacrococcygeal neoplasms for local control or palliation of pain in this small series with short-term follow-up.

AB - Purpose: To review the safety and efficacy of cryoablation of recurrent sacrococcygeal tumors. Materials and Methods: The radiology departmental ablation database was retrospectively searched for cases of cryoablation performed to treat recurrences of sacrococcygeal tumors between January 1, 2010, and August 1, 2011. Patient demographics, procedure technical parameters, and patient outcomes were reviewed. Results: Five cases of recurrent chordoma and one recurrent myxopapillary ependymoma were treated with cryoablation in six patients whose ages ranged from 31 to 80 years. The tumors measured 14-39 mm in maximal dimension. Cryoablation was performed with the use of computed tomography guidance (n = 5) or a combination of ultrasound and magnetic resonance imaging guidance (n = 1). Sterile fluid was instilled to displace adjacent bowel and/or vagina in four cases, and electromyography monitoring was performed in two cases with adjacent nerve roots. Two patients with recurrent chordoma were treated for palliation of pain, with complete pain relief in one patient (pain recurred after 6 wk) and immediate reduction in pain from a score of six to a score of two on a 10-point scale in the other (pain recurred after 7 mo). Four tumors were treated for local control, with no evidence of recurrence on follow-up imaging at 3, 6, 12, and 15 months. No serious complication occurred. Conclusions: Limited results suggest cryoablation to be a safe and relatively effective means of treating recurrent sacrococcygeal neoplasms for local control or palliation of pain in this small series with short-term follow-up.

KW - radiation therapy

KW - RT

UR - http://www.scopus.com/inward/record.url?scp=84864269163&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84864269163&partnerID=8YFLogxK

U2 - 10.1016/j.jvir.2012.05.043

DO - 10.1016/j.jvir.2012.05.043

M3 - Article

C2 - 22840806

AN - SCOPUS:84864269163

VL - 23

SP - 1070

EP - 1075

JO - Journal of Vascular and Interventional Radiology

JF - Journal of Vascular and Interventional Radiology

SN - 1051-0443

IS - 8

ER -