Crohn's disease of the ileoanal pouch

Amy Lightner, John H. Pemberton, Edward Vincent Loftus, Jr

Research output: Contribution to journalReview article

15 Citations (Scopus)

Abstract

Crohn's disease (CD) of the pouch is an increasingly recognized diagnosis after ileal pouch-anal anastomosis. This post-ileal pouch-anal anastomosis diagnosis in conjunction with pouchitis remains the leading reason for pouch excision. Unfortunately, CD of the pouch remains a difficult diagnosis with lack of a uniform definition largely because of its similarity to common postoperative pouch complications, including pouchitis, abscess formation, or stricture at the anastomosis. Once diagnosed, treatment algorithms largely include multimodal therapy including biologics. This review focuses on the definition, etiology, diagnosis, and treatment for CD of the pouch, a postoperative de novo diagnosis of CD.

Original languageEnglish (US)
Pages (from-to)1502-1508
Number of pages7
JournalInflammatory Bowel Diseases
Volume22
Issue number6
DOIs
StatePublished - Jun 1 2016

Fingerprint

Colonic Pouches
Crohn Disease
Pouchitis
Biological Therapy
Abscess
Pathologic Constriction
Therapeutics

Keywords

  • CD of the pouch
  • Crohn's disease
  • IPAA
  • pouchitis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Medicine(all)
  • Gastroenterology

Cite this

Crohn's disease of the ileoanal pouch. / Lightner, Amy; Pemberton, John H.; Loftus, Jr, Edward Vincent.

In: Inflammatory Bowel Diseases, Vol. 22, No. 6, 01.06.2016, p. 1502-1508.

Research output: Contribution to journalReview article

Lightner, Amy ; Pemberton, John H. ; Loftus, Jr, Edward Vincent. / Crohn's disease of the ileoanal pouch. In: Inflammatory Bowel Diseases. 2016 ; Vol. 22, No. 6. pp. 1502-1508.
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