Crohn’s disease diagnosis, treatment approach, and management paradigm: what the radiologist needs to know

Parakkal Deepak, Sang Hyoung Park, Eric Ehman, Stephanie L. Hansel, Jeff L. Fidler, David H Bruining, Joel Garland Fletcher

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Crohn’s disease is one of the major subtypes of idiopathic inflammatory bowel disease and is characterized by chronic transmural intestinal inflammation of the gastrointestinal tract anywhere from mouth to the anus, with a predilection for the small bowel. Cross-sectional imaging with computed tomography and magnetic resonance enterography plays a key role in confirming diagnosis, identifying and managing complications, assessing disease severity, and identifying response to medical therapy. This review will focus on the role of radiologists in the diagnosis and assessment of Crohn’s disease. Additionally, a review of current medical therapy approaches, available medications, and side effects will be discussed. The review will also highlight key complications of medical therapy and associated diseases that should be evaluated by the radiologist with cross-sectional imaging.

Original languageEnglish (US)
Pages (from-to)1068-1086
Number of pages19
JournalAbdominal Radiology
Volume42
Issue number4
DOIs
StatePublished - Apr 1 2017

Keywords

  • Computed
  • Crohn’s disease management
  • Magnetic resonance imaging
  • Tomography
  • Tumor necrosis factor-alpha/antagonists and inhibitors
  • X-ray

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology
  • Radiological and Ultrasound Technology

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