Crizotinib-associated renal cyst development may be associated with prolonged progression-free survival in patients with ALK-positive non-small-cell lung cancer: Case report and review of the literature

Nathaniel E. Wiest; Katherine S. Tzou; Matthew T. Olson; Steven M. Herchko; Essa M. Bajalia; David D. Thiel; Yanyan Lou; Yujie Zhao; Rami Manochakian

doi:10.1002/ccr3.4278

Crizotinib-associated renal cyst development may be associated with prolonged progression-free survival in patients with ALK-positive non-small-cell lung cancer: Case report and review of the literature

Nathaniel E. Wiest, Katherine S. Tzou, Matthew T. Olson, Steven M. Herchko, Essa M. Bajalia, David D. Thiel, Yanyan Lou, Yujie Zhao, Rami Manochakian

Hematology / Oncology / Cancer Center / Breast Clinic

Research output: Contribution to journal › Article › peer-review

Abstract

Non-small cell lung cancer patients with anaplastic lymphoma kinase or c-ros oncogene 1 mutations who are treated with the tyrosine kinase inhibitor crizotinib rarely develop crizotinib-associated renal cysts (CARCs). Here, we present a case report and review of the literature supporting the hypothesis that CARCs may correlate positively with progression-free survival.

Original language	English (US)
Article number	e04278
Journal	Clinical Case Reports
Volume	9
Issue number	6
DOIs	https://doi.org/10.1002/ccr3.4278
State	Published - Jun 2021

Keywords

ALK positive
crizotinib
non-small-cell lung cancer
progression-free survival
renal cysts

ASJC Scopus subject areas

General Medicine

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10.1002/ccr3.4278

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Wiest, N. E., Tzou, K. S., Olson, M. T., Herchko, S. M., Bajalia, E. M., Thiel, D. D., Lou, Y., Zhao, Y., & Manochakian, R. (2021). Crizotinib-associated renal cyst development may be associated with prolonged progression-free survival in patients with ALK-positive non-small-cell lung cancer: Case report and review of the literature. Clinical Case Reports, 9(6), Article e04278. https://doi.org/10.1002/ccr3.4278

Crizotinib-associated renal cyst development may be associated with prolonged progression-free survival in patients with ALK-positive non-small-cell lung cancer: Case report and review of the literature. / Wiest, Nathaniel E.; Tzou, Katherine S.; Olson, Matthew T. et al.
In: Clinical Case Reports, Vol. 9, No. 6, e04278, 06.2021.

Research output: Contribution to journal › Article › peer-review

Wiest, NE, Tzou, KS, Olson, MT, Herchko, SM, Bajalia, EM, Thiel, DD, Lou, Y, Zhao, Y & Manochakian, R 2021, 'Crizotinib-associated renal cyst development may be associated with prolonged progression-free survival in patients with ALK-positive non-small-cell lung cancer: Case report and review of the literature', Clinical Case Reports, vol. 9, no. 6, e04278. https://doi.org/10.1002/ccr3.4278

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title = "Crizotinib-associated renal cyst development may be associated with prolonged progression-free survival in patients with ALK-positive non-small-cell lung cancer: Case report and review of the literature",

abstract = "Non-small cell lung cancer patients with anaplastic lymphoma kinase or c-ros oncogene 1 mutations who are treated with the tyrosine kinase inhibitor crizotinib rarely develop crizotinib-associated renal cysts (CARCs). Here, we present a case report and review of the literature supporting the hypothesis that CARCs may correlate positively with progression-free survival.",

keywords = "ALK positive, crizotinib, non-small-cell lung cancer, progression-free survival, renal cysts",

author = "Wiest, {Nathaniel E.} and Tzou, {Katherine S.} and Olson, {Matthew T.} and Herchko, {Steven M.} and Bajalia, {Essa M.} and Thiel, {David D.} and Yanyan Lou and Yujie Zhao and Rami Manochakian",

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year = "2021",

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AU - Wiest, Nathaniel E.

AU - Tzou, Katherine S.

AU - Olson, Matthew T.

AU - Herchko, Steven M.

AU - Bajalia, Essa M.

AU - Thiel, David D.

AU - Lou, Yanyan

AU - Zhao, Yujie

AU - Manochakian, Rami

PY - 2021/6

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N2 - Non-small cell lung cancer patients with anaplastic lymphoma kinase or c-ros oncogene 1 mutations who are treated with the tyrosine kinase inhibitor crizotinib rarely develop crizotinib-associated renal cysts (CARCs). Here, we present a case report and review of the literature supporting the hypothesis that CARCs may correlate positively with progression-free survival.

AB - Non-small cell lung cancer patients with anaplastic lymphoma kinase or c-ros oncogene 1 mutations who are treated with the tyrosine kinase inhibitor crizotinib rarely develop crizotinib-associated renal cysts (CARCs). Here, we present a case report and review of the literature supporting the hypothesis that CARCs may correlate positively with progression-free survival.

KW - ALK positive

KW - crizotinib

KW - non-small-cell lung cancer

KW - progression-free survival

KW - renal cysts

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Crizotinib-associated renal cyst development may be associated with prolonged progression-free survival in patients with ALK-positive non-small-cell lung cancer: Case report and review of the literature

Abstract

Keywords

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