Critical review and state of the art in interventional oncology

Benign and metastatic disease involving bone

Daniel Rosenthal, Matthew R Callstrom

Research output: Contribution to journalArticle

88 Citations (Scopus)

Abstract

Image-guided percutaneous ablation methods have proved effective for treatment of benign bone tumors and for palliation of metastases involving bone and soft-tissue sites beyond the liver and lung. Image-guided radiofrequency ablation is now the standard treatment for osteoid osteoma, as the procedure can be performed with higher rates of technical success, decreased morbidity, and lower cost than those obtained with open surgery. Several ablation methods have been used to effectively palliate focal painful metastatic disease involving bone and soft-tissue sites beyond the liver and lung. Substantial pain reduction is possible in patients who have failed to achieve benefit from conventional therapies, including chemotherapy and external-beam radiation. Importantly, the pain reduction that is achieved is durable over many months of observation.

Original languageEnglish (US)
Pages (from-to)765-780
Number of pages16
JournalRadiology
Volume262
Issue number3
DOIs
StatePublished - Mar 2012

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Bone Diseases
Bone and Bones
Osteoid Osteoma
Pain
Lung
Liver
Therapeutics
Observation
Radiation
Neoplasm Metastasis
Morbidity
Costs and Cost Analysis
Drug Therapy
Neoplasms

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Critical review and state of the art in interventional oncology : Benign and metastatic disease involving bone. / Rosenthal, Daniel; Callstrom, Matthew R.

In: Radiology, Vol. 262, No. 3, 03.2012, p. 765-780.

Research output: Contribution to journalArticle

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