Critical illness weakness: Common questions

Konstantinos Linos, Carole Foot, Marc Ziegenfuss, W. David Freeman, K. Meng Tan

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Weakness is a common problem in patients requiring intensive care unit management. Critical illness polyneuromyopathy is a useful term to describe the acquired neuropathy and/or myopathy that develops in the setting of critical illness. There is a broad differential diagnosis and although most cases can be diagnosed clinically, a range of investigations may be required. The principal risk factors are systemic inflammatory response syndrome (particularly due to severe sepsis), corticosteroid and neuromuscular blocking drug administration and hyperglycaemia. Treatment remains largely supportive, emphasizing the importance of preventative strategies. This article will answer common questions pertaining to critical illness weakness.

Original languageEnglish (US)
Pages (from-to)252-260
Number of pages9
JournalCurrent Anaesthesia and Critical Care
Issue number5-6
StatePublished - Dec 5 2007


  • Critical illness
  • Critical illness myopathy
  • Critical illness polyneuropathy
  • Polyneuropathy

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Anesthesiology and Pain Medicine


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