Abstract
The authors describe an unusual case of acute renal failure in a 50-year-old woman with a history of breast carcinoma. The breast carcinoma was treated with 4 cycles of chemotherapy. After chemotherapy, she felt fatigued and noticed decreased urine output. Her serum creatinine level had risen from 0.8 to 10.1 mg/dL (71 to 893 μmol/L). Renal biopsy was done that showed a severe crescentic glomerulonephritis secondary to dense deposit disease. This case is extremely unusual in that: (1) Dense deposit disease developed in a 50-year-old woman, whereas it is primarily a disease of children and young adults, and (2) the patient was being treated with immunosuppressive chemotherapy for breast carcinoma when dense deposit disease developed, thus posing a therapeutic dilemma.
Original language | English (US) |
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Pages (from-to) | e33-e37 |
Journal | American Journal of Kidney Diseases |
Volume | 44 |
Issue number | 3 |
DOIs | |
State | Published - Sep 2004 |
Keywords
- Dense deposit disease
- breast carcinoma
- crescentic glomerulonephritis
ASJC Scopus subject areas
- Nephrology