Abstract
We observed myoclonic movements of the fingers and wrists in two patients with a levodopa-responsive parkinsonian syndrome most consistent with Parkinson's disease. These patients were studied with electrophysiological techniques. Brief (< 50 ms) myoclonic electromyographic discharges showed a time-locked relationship to a focal premovement electroencephalographic potential. Somatosensory-evoked potentials were not enlarged and long-latency reflexes were not grossly exaggerated. This pattern of electrophysiological findings can be distinguished from those previously found in other parkinsonian syndromes. These results provide evidence for a cortical origin of the myoclonus seen in these patients.
Original language | English (US) |
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Pages (from-to) | 540-544 |
Number of pages | 5 |
Journal | Movement Disorders |
Volume | 13 |
Issue number | 3 |
DOIs | |
State | Published - May 1998 |
Keywords
- Cortex
- Electrophysiology
- Myoclonus
- Parkinson's disease
- Parkinsonism
ASJC Scopus subject areas
- Neurology
- Clinical Neurology