Abstract
Background: The Movement Disorder Society’s Unified Parkinson’s Disease Rating Scale (MDS-UPDRS), Scales for Outcomes in Parkinson’s Disease–Autonomic (SCOPA-AUT), Mayo Sleep Questionnaire, Epworth Sleepiness Scale, and Neuropsychiatric Inventory Questionnaire (NPI-Q) are validated instruments for assessing signs and symptoms of Parkinson’s disease (PD). Objective: We sought to determine whether responses on the MDS-UPDRS correlate with responses to other scales used in patients with PD. Design: Study subjects were enrolled in the Arizona Study of Aging and Neurodegenerative Disorders (AZSAND). Participants were selected if they had completed all scales within a one-month window. Spearman’s rank correlation coefficients were calculated. Results: A total of 96 eligible subjects were identified. High correlation (r-values) was found between the SCOPA-AUT and MDS-UPDRS excessive saliva (0.73; p<0.001), constipation (0.62; p<0.001), and swallowing (0.59; p<0.001) questions. The r-values for the NPI-Q and MDS-UPDRS depression and anxiety questions were 0.53 (p<0.001), and 0.67 (p<0.001). Conclusion: MDS-UPDRS correlates well with some but not all questions from the SCOPA-AUT and NPI-Q. This work emphasizes the importance of employing multiple methods for assessing nonmotor symptoms in patients with PD.
Original language | English (US) |
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Pages (from-to) | 27-29 |
Number of pages | 3 |
Journal | Innovations in Clinical Neuroscience |
Volume | 16 |
Issue number | 9-10 |
State | Published - Sep 1 2019 |
Keywords
- ESS
- MDS-UPDRS
- MSQ
- NPI-Q
- Parkinson’s disease
- SCOPA-AUT
ASJC Scopus subject areas
- Clinical Neurology
- Psychiatry and Mental health