Correlation between intraoperative blood flows and hepatic artery strictures in liver transplantation

Ernesto P. Molmenti, Marlon F. Levy, Hebe Molmenti, Donna Casey, Carlos G. Fasola, W. Mark Hamilton, Ghapjoong Jung, Shigeru Marubashi, Brian M. Gogel, Robert M. Goldstein, Thomas A. Gonwa, Goran B. Klintmalm

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Hepatic artery strictures (HASs) may be a source of morbidity and mortality in liver transplant recipients. This study evaluated the potential correlation between intraoperative arterial and venous blood flows measured after implantation of the liver allograft and the occurrence of postoperative HASs requiring repair. Prospectively collected data from 1,038 patients with complete data sets who underwent initial orthotopic liver transplantations between December 1984 and December 1999 were used. Electromagnetic flow measurements were routinely obtained in these cases. Hepatic artery and portal vein patency were reassessed routinely according to our protocol in the first postoperative day by Doppler ultrasound. When considered hemodynamically significant, strictures were corrected. There was a 6.2% incidence (n = 64) of hepatic artery stenosis in our transplant population. When considered as a whole, the hepatic artery stenosis group had lower intraoperative flow volumes than transplant recipients who did not develop strictures (mean flows, 452 v 518 mL/min, respectively; P = .025). The hepatic artery stenosis group also had lower intraoperative portal vein flows compared with the group without hepatic artery stenosis (1.80 v 2.11 L/min, respectively; P = .0043). Strictures were less frequent among transplant recipients with cryptogenic cirrhosis. We did not observe differences among the groups for retransplantation or patient and graft survival. In our series, there was a 6.2% incidence of postoperative HASs. We observed a significant association between intraoperative hepatic artery and portal vein flows and postoperative HASs.

Original languageEnglish (US)
Pages (from-to)160-163
Number of pages4
JournalLiver Transplantation
Volume8
Issue number2
DOIs
StatePublished - 2002
Externally publishedYes

Fingerprint

Hepatic Artery
Liver Transplantation
Pathologic Constriction
Portal Vein
Hepatic Veins
Doppler Ultrasonography
Electromagnetic Phenomena
Liver
Incidence
Graft Survival
Allografts
Morbidity
Transplants

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Molmenti, E. P., Levy, M. F., Molmenti, H., Casey, D., Fasola, C. G., Hamilton, W. M., ... Klintmalm, G. B. (2002). Correlation between intraoperative blood flows and hepatic artery strictures in liver transplantation. Liver Transplantation, 8(2), 160-163. https://doi.org/10.1053/jlts.2002.30886

Correlation between intraoperative blood flows and hepatic artery strictures in liver transplantation. / Molmenti, Ernesto P.; Levy, Marlon F.; Molmenti, Hebe; Casey, Donna; Fasola, Carlos G.; Hamilton, W. Mark; Jung, Ghapjoong; Marubashi, Shigeru; Gogel, Brian M.; Goldstein, Robert M.; Gonwa, Thomas A.; Klintmalm, Goran B.

In: Liver Transplantation, Vol. 8, No. 2, 2002, p. 160-163.

Research output: Contribution to journalArticle

Molmenti, EP, Levy, MF, Molmenti, H, Casey, D, Fasola, CG, Hamilton, WM, Jung, G, Marubashi, S, Gogel, BM, Goldstein, RM, Gonwa, TA & Klintmalm, GB 2002, 'Correlation between intraoperative blood flows and hepatic artery strictures in liver transplantation', Liver Transplantation, vol. 8, no. 2, pp. 160-163. https://doi.org/10.1053/jlts.2002.30886
Molmenti, Ernesto P. ; Levy, Marlon F. ; Molmenti, Hebe ; Casey, Donna ; Fasola, Carlos G. ; Hamilton, W. Mark ; Jung, Ghapjoong ; Marubashi, Shigeru ; Gogel, Brian M. ; Goldstein, Robert M. ; Gonwa, Thomas A. ; Klintmalm, Goran B. / Correlation between intraoperative blood flows and hepatic artery strictures in liver transplantation. In: Liver Transplantation. 2002 ; Vol. 8, No. 2. pp. 160-163.
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