Correction of factor XI deficiency by liver transplantation

Eva Gupta, Laura Finn, Gretchen Johns, Rajiv K. Pruthi, Vivek Roy

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Orthotopic liver transplantation for other diseases typically results in a coincidental cure for hemophilia A and B; however, long-term outcomes of liver transplant in hemophilia C are not very well described. Herein, the authors report a patient of severe congenital factor XI (FXI) deficiency who received an orthotopic liver transplant. The authors discuss the perioperative management and long-term outcomes. The normalization of his FXI levels confirms that the liver is the most clinically relevant site of synthesis of FXI.

Original languageEnglish (US)
Pages (from-to)961-963
Number of pages3
JournalBlood Coagulation and Fibrinolysis
Volume26
Issue number8
DOIs
StatePublished - 2015
Externally publishedYes

Keywords

  • Bleeding
  • Clotting factors
  • Factor XI deficiency
  • Hemophilia
  • Liver transplant

ASJC Scopus subject areas

  • Hematology

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