Coronary intervention in thrombus-rich lesions: Beyond stents and glycoprotein IIb/IIIa inhibitors

Amir Halkin, Gad Keren, Gregg W. Stone, David R. Holmes, Uri Rosenschein

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Despite widespread use of stents and GP IIb/IIIa antagonists, complications following percutaneous treatment of thrombus-rich lesions continue to plague patients with ACS. In these patients the angiographically evident coronary thrombosis may represent a high degree of thrombus burden, which leads to a higher level of microembolization and its clinical sequelae. New catheter-based thrombus burden reduction systems and distal protection devices show promise for improving the prognosis of these high risk patients by decreasing distal microembolization, and thereby preventing myonecrosis. Careful procedural timing and patient selection are also likely to improve outcomes and resource utilization in the management of ACS patients.

Original languageEnglish (US)
Pages (from-to)795-800
Number of pages6
JournalIsrael Medical Association Journal
Issue number11
StatePublished - Nov 1 2003


  • Acute myocardial infarction
  • Microcirculation
  • Microembolization
  • Perfusion
  • Thrombus

ASJC Scopus subject areas

  • Medicine(all)

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