Coronary intervention in thrombus-rich lesions: Beyond stents and glycoprotein IIb/IIIa inhibitors

Amir Halkin, Gad Keren, Gregg W. Stone, David Holmes, Uri Rosenschein

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Despite widespread use of stents and GP IIb/IIIa antagonists, complications following percutaneous treatment of thrombus-rich lesions continue to plague patients with ACS. In these patients the angiographically evident coronary thrombosis may represent a high degree of thrombus burden, which leads to a higher level of microembolization and its clinical sequelae. New catheter-based thrombus burden reduction systems and distal protection devices show promise for improving the prognosis of these high risk patients by decreasing distal microembolization, and thereby preventing myonecrosis. Careful procedural timing and patient selection are also likely to improve outcomes and resource utilization in the management of ACS patients.

Original languageEnglish (US)
Pages (from-to)795-800
Number of pages6
JournalIsrael Medical Association Journal
Volume5
Issue number11
StatePublished - Nov 1 2003

Fingerprint

Platelet Glycoprotein GPIIb-IIIa Complex
Stents
Thrombosis
Platelet Membrane Glycoprotein IIb
Coronary Thrombosis
Plague
Patient Selection
Catheters
Equipment and Supplies
Therapeutics

Keywords

  • Acute myocardial infarction
  • Microcirculation
  • Microembolization
  • Perfusion
  • Thrombus

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Coronary intervention in thrombus-rich lesions : Beyond stents and glycoprotein IIb/IIIa inhibitors. / Halkin, Amir; Keren, Gad; Stone, Gregg W.; Holmes, David; Rosenschein, Uri.

In: Israel Medical Association Journal, Vol. 5, No. 11, 01.11.2003, p. 795-800.

Research output: Contribution to journalReview article

Halkin, Amir ; Keren, Gad ; Stone, Gregg W. ; Holmes, David ; Rosenschein, Uri. / Coronary intervention in thrombus-rich lesions : Beyond stents and glycoprotein IIb/IIIa inhibitors. In: Israel Medical Association Journal. 2003 ; Vol. 5, No. 11. pp. 795-800.
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