Coronary artery disease: Development and progression

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Over the past decades the term Coronary Artery Disease (CAD) epitomized the involvement of the epicardial coronary circulation in the atherosclerotic disease process, classically in conjunction with the visualization of luminal narrowing by angiography. However, a disease state of the coronary arteries can develop independently from the systemic atherosclerotic disease process, for instance, as part of a vasculitis syndrome such as Kawasaki disease or systemic diseases such as amyloidosis. Moreover, CAD functionally involves the entire coronary circulation, including the myocardial microvasculature. This chapter will review CAD as part of the atherosclerotic cardiovascular disease (ASCVD) process. Specifically, it will focus on current concepts of its pathophysiology as it underlies clinical presentation and therapy.

Original languageEnglish (US)
Title of host publicationCoronary Artery Disease: New Approaches without Traditional Revascularization
PublisherSpringer-Verlag London Ltd
Pages21-28
Number of pages8
Volume9781846287121
ISBN (Print)9781846287121, 1846284600, 9781846284601
DOIs
StatePublished - Apr 1 2014

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Herrmann, J., & Lerman, A. (2014). Coronary artery disease: Development and progression. In Coronary Artery Disease: New Approaches without Traditional Revascularization (Vol. 9781846287121, pp. 21-28). Springer-Verlag London Ltd. https://doi.org/10.1007/978-1-84628-712-1_3