Convenient synthesis of a library of discrete hydroxamic acids using the hydroxythiophenol (Marshall) resin

Jinil Choi, Jewn Giew Park, Yuan Ping Pang

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Several resins have reportedly been used to synthesize hydroxamic acids except for the hydroxythiophenol (Marshall) resin. Herein, we report the use of the Marshall resin to synthesize hydroxamic acids from carboxylic acids and its application to convert a library of 14 discrete aliphatic and aromatic carboxylic acids including N-protected amino acids to their corresponding hydroxamic acids in good yields.

Original languageEnglish (US)
Pages (from-to)1103-1106
Number of pages4
JournalTetrahedron Letters
Volume49
Issue number7
DOIs
StatePublished - Feb 11 2008

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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