Abstract
Diabetic patients with coronary artery disease are common and complex, with an aggressive progression of atherosclerosis, increased rate of stent complications, and increased rates of incomplete revascularization in multivessel disease compared to non-diabetic patients. In this review, we first discuss the pathophysiologic elements of insulin resistance and presentations of coronary artery disease in diabetic patients. Next, we outline the evolution and present the data on revascularization strategies on diabetic patient outcomes. The overall conclusion of our review is that a strategy of complete and durable revascularization and guideline-directed medical therapy currently provides the best possible chance at closing the gap between outcomes in patients with and without diabetes.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 633-648 |
| Number of pages | 16 |
| Journal | Expert Review of Cardiovascular Therapy |
| Volume | 14 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 3 2016 |
Keywords
- BARI2D
- Cabg
- DES
- PCI
- bare metal stent
- complete revascularization
- diabetes
- drug-eluting stent
- hybrid revascularization
- syntax
ASJC Scopus subject areas
- Internal Medicine
- Cardiology and Cardiovascular Medicine