Controversies surrounding percutaneous coronary intervention in the diabetic patient

Sara C. Martinez, David R. Holmes

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Diabetic patients with coronary artery disease are common and complex, with an aggressive progression of atherosclerosis, increased rate of stent complications, and increased rates of incomplete revascularization in multivessel disease compared to non-diabetic patients. In this review, we first discuss the pathophysiologic elements of insulin resistance and presentations of coronary artery disease in diabetic patients. Next, we outline the evolution and present the data on revascularization strategies on diabetic patient outcomes. The overall conclusion of our review is that a strategy of complete and durable revascularization and guideline-directed medical therapy currently provides the best possible chance at closing the gap between outcomes in patients with and without diabetes.

Original languageEnglish (US)
Pages (from-to)633-648
Number of pages16
JournalExpert Review of Cardiovascular Therapy
Issue number5
StatePublished - May 3 2016


  • BARI2D
  • Cabg
  • DES
  • PCI
  • bare metal stent
  • complete revascularization
  • diabetes
  • drug-eluting stent
  • hybrid revascularization
  • syntax

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine


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