Contrast dobutamine stress echocardiography: Clinical practice assessment in 300 consecutive patients

Andrew J. Rainbird, Sharon L. Mulvagh, Jae K. Oh, Robert B. McCully, Kyle W. Klarich, Clarence Shub, Douglas W. Mahoney, Patricia A. Pellikka

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116 Scopus citations


In this study we compared non-contrast imaging with contrast imaging of the left ventricle during dobutamine stress echocardiography (DSE). Wall segment visualization, image quality, and confidence of interpretation were determined with and without the use of intravenous Optison, a secondgeneration echocardiographic contrast agent, in 300 consecutive patients undergoing rest and peak DSE. At rest and at peak stress, the percentage of wall segments visualized, image quality, and confidence of interpretation were better with contrast compared with non-contrast imaging. No significant decrease was seen in wall segment visualization, image quality, or confidence of interpretation from rest to peak stress in images obtained with contrast, unlike the images obtained without contrast from rest to peak stress. The use of the intravenous echocardiographic contrast agent Optison during DSE significantly improved wall segment visualization and image quality at rest and at peak stress, resulting in improved confidence of interpretation.

Original languageEnglish (US)
Pages (from-to)378-385
Number of pages8
JournalJournal of the American Society of Echocardiography
Issue number5
StatePublished - Jan 1 2001


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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