Continuous neomycin production by immobilized cells of Streptomyces marinensis NUV-5 in an airlift bioreactor

Research output: Contribution to journalArticlepeer-review

Abstract

Neomycin production by free and calcium alginate immobilized cells was investigated in an airlift reactor. The average volumetric productivity with continuous fermentation (72.97 mg/l/h) was greater than with free cells (45.05 mg/l/h). The total neomycin produced with continuous fermentation was 62% greater than with that of free cells. Immobilized Streptomyces particles showed a half-life of 42 days during continuous fermentation under airlift conditions.

Original languageEnglish (US)
Pages (from-to)1407-1414
Number of pages8
JournalProcess Biochemistry
Volume39
Issue number11
DOIs
StatePublished - Jul 30 2004

Keywords

  • Airlift reactor
  • Continuous fermentation
  • Neomycin
  • Streptomyces marinensis NUV-5

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Applied Microbiology and Biotechnology

Fingerprint

Dive into the research topics of 'Continuous neomycin production by immobilized cells of Streptomyces marinensis NUV-5 in an airlift bioreactor'. Together they form a unique fingerprint.

Cite this