Consequences of restenosis after coronary angioplasty

Ronald E. Vlietstra, David Holmes, Richard J. Rodeheffer, Kent R Bailey

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The consequences of restenosis after angioplasty were evaluated in 466 patients who had coronary angiography 3 to 12 months after successful coronary angioplasty and were followed long term. The 236 subjects with restenosis resembled the 230 without restenosis with respect to age, sex, presence of multivessel disease, mean ejection fraction, prior myocardial infarction, prior coronary artery bypass grafting, and completeness of revascularization. The 5-year relative risk of revascularization for patients with restenosis markedly exceeded that for patients without restenosis. The relative risk of repeat angioplasty in the former group was 4.26 times that in the latter group (95% confidence interval, 2.80 to 6.51), and the risk of coronary artery bypass grafting in patients with restenosis was 3.68 (95% confidence interval, 2.16 to 6.28). There was no difference between the 2 groups in the relative risk of myocardial infarction or death. When the completeness of revascularization was considered, patients with incomplete revascularization and restenosis had the worst outcomes, with 50% needing coronary artery bypass grafting within 5 years. Early restenosis markedly increases the probability of revascularization, but it has little effect on infarction or mortality. Even when early restenosis is absent, further revascularization procedures are still frequent. A solution to the problem of restenosis might reduce by half the need for revascularization during the subsequent 5 years.

Original languageEnglish (US)
Pages (from-to)143-147
Number of pages5
JournalInternational Journal of Cardiology
Volume31
Issue number2
DOIs
StatePublished - 1991

Fingerprint

Coronary Restenosis
Angioplasty
Coronary Artery Bypass
Myocardial Infarction
Confidence Intervals
Coronary Angiography
Infarction
Mortality

Keywords

  • Coronary angioplasty
  • Post-angioplasty restenosis
  • Restenosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Consequences of restenosis after coronary angioplasty. / Vlietstra, Ronald E.; Holmes, David; Rodeheffer, Richard J.; Bailey, Kent R.

In: International Journal of Cardiology, Vol. 31, No. 2, 1991, p. 143-147.

Research output: Contribution to journalArticle

Vlietstra, Ronald E. ; Holmes, David ; Rodeheffer, Richard J. ; Bailey, Kent R. / Consequences of restenosis after coronary angioplasty. In: International Journal of Cardiology. 1991 ; Vol. 31, No. 2. pp. 143-147.
@article{c77433dd4b794d5e89e6a3f659de5ee4,
title = "Consequences of restenosis after coronary angioplasty",
abstract = "The consequences of restenosis after angioplasty were evaluated in 466 patients who had coronary angiography 3 to 12 months after successful coronary angioplasty and were followed long term. The 236 subjects with restenosis resembled the 230 without restenosis with respect to age, sex, presence of multivessel disease, mean ejection fraction, prior myocardial infarction, prior coronary artery bypass grafting, and completeness of revascularization. The 5-year relative risk of revascularization for patients with restenosis markedly exceeded that for patients without restenosis. The relative risk of repeat angioplasty in the former group was 4.26 times that in the latter group (95{\%} confidence interval, 2.80 to 6.51), and the risk of coronary artery bypass grafting in patients with restenosis was 3.68 (95{\%} confidence interval, 2.16 to 6.28). There was no difference between the 2 groups in the relative risk of myocardial infarction or death. When the completeness of revascularization was considered, patients with incomplete revascularization and restenosis had the worst outcomes, with 50{\%} needing coronary artery bypass grafting within 5 years. Early restenosis markedly increases the probability of revascularization, but it has little effect on infarction or mortality. Even when early restenosis is absent, further revascularization procedures are still frequent. A solution to the problem of restenosis might reduce by half the need for revascularization during the subsequent 5 years.",
keywords = "Coronary angioplasty, Post-angioplasty restenosis, Restenosis",
author = "Vlietstra, {Ronald E.} and David Holmes and Rodeheffer, {Richard J.} and Bailey, {Kent R}",
year = "1991",
doi = "10.1016/0167-5273(91)90208-7",
language = "English (US)",
volume = "31",
pages = "143--147",
journal = "International Journal of Cardiology",
issn = "0167-5273",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

TY - JOUR

T1 - Consequences of restenosis after coronary angioplasty

AU - Vlietstra, Ronald E.

AU - Holmes, David

AU - Rodeheffer, Richard J.

AU - Bailey, Kent R

PY - 1991

Y1 - 1991

N2 - The consequences of restenosis after angioplasty were evaluated in 466 patients who had coronary angiography 3 to 12 months after successful coronary angioplasty and were followed long term. The 236 subjects with restenosis resembled the 230 without restenosis with respect to age, sex, presence of multivessel disease, mean ejection fraction, prior myocardial infarction, prior coronary artery bypass grafting, and completeness of revascularization. The 5-year relative risk of revascularization for patients with restenosis markedly exceeded that for patients without restenosis. The relative risk of repeat angioplasty in the former group was 4.26 times that in the latter group (95% confidence interval, 2.80 to 6.51), and the risk of coronary artery bypass grafting in patients with restenosis was 3.68 (95% confidence interval, 2.16 to 6.28). There was no difference between the 2 groups in the relative risk of myocardial infarction or death. When the completeness of revascularization was considered, patients with incomplete revascularization and restenosis had the worst outcomes, with 50% needing coronary artery bypass grafting within 5 years. Early restenosis markedly increases the probability of revascularization, but it has little effect on infarction or mortality. Even when early restenosis is absent, further revascularization procedures are still frequent. A solution to the problem of restenosis might reduce by half the need for revascularization during the subsequent 5 years.

AB - The consequences of restenosis after angioplasty were evaluated in 466 patients who had coronary angiography 3 to 12 months after successful coronary angioplasty and were followed long term. The 236 subjects with restenosis resembled the 230 without restenosis with respect to age, sex, presence of multivessel disease, mean ejection fraction, prior myocardial infarction, prior coronary artery bypass grafting, and completeness of revascularization. The 5-year relative risk of revascularization for patients with restenosis markedly exceeded that for patients without restenosis. The relative risk of repeat angioplasty in the former group was 4.26 times that in the latter group (95% confidence interval, 2.80 to 6.51), and the risk of coronary artery bypass grafting in patients with restenosis was 3.68 (95% confidence interval, 2.16 to 6.28). There was no difference between the 2 groups in the relative risk of myocardial infarction or death. When the completeness of revascularization was considered, patients with incomplete revascularization and restenosis had the worst outcomes, with 50% needing coronary artery bypass grafting within 5 years. Early restenosis markedly increases the probability of revascularization, but it has little effect on infarction or mortality. Even when early restenosis is absent, further revascularization procedures are still frequent. A solution to the problem of restenosis might reduce by half the need for revascularization during the subsequent 5 years.

KW - Coronary angioplasty

KW - Post-angioplasty restenosis

KW - Restenosis

UR - http://www.scopus.com/inward/record.url?scp=0025907283&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025907283&partnerID=8YFLogxK

U2 - 10.1016/0167-5273(91)90208-7

DO - 10.1016/0167-5273(91)90208-7

M3 - Article

C2 - 1869321

AN - SCOPUS:0025907283

VL - 31

SP - 143

EP - 147

JO - International Journal of Cardiology

JF - International Journal of Cardiology

SN - 0167-5273

IS - 2

ER -