Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases

James R. Stone, Patrick Bruneval, Annalisa Angelini, Giovanni Bartoloni, Cristina Basso, Lubov Batoroeva, L. Maximilian Buja, Jagdish Butany, Giulia D'Amati, John T. Fallon, Adriana C. Gittenberger-De Groot, Rosa H. Gouveia, Marc K. Halushka, Karen L. Kelly, Ivana Kholova, Ornella Leone, Silvio H. Litovsky, Joseph J. Maleszewski, Dylan V. Miller, Richard N. MitchellStephen D. Preston, Angela Pucci, Stanley J. Radio, E. Rene Rodriguez, Mary N. Sheppard, S. Kim Suvarna, Carmela D. Tan, Gaetano Thiene, Allard C. Van Der Wal, John P. Veinot

Research output: Contribution to journalReview article

93 Scopus citations

Abstract

Inflammatory diseases of the aorta include routine atherosclerosis, aortitis, periaortitis, and atherosclerosis with excessive inflammatory responses, such as inflammatory atherosclerotic aneurysms. The nomenclature and histologic features of these disorders are reviewed and discussed. In addition, diagnostic criteria are provided to distinguish between these disorders in surgical pathology specimens. An initial classification scheme is provided for aortitis and periaortitis based on the pattern of the inflammatory infiltrate: granulomatous/giant cell pattern, lymphoplasmacytic pattern, mixed inflammatory pattern, and the suppurative pattern. These inflammatory patterns are discussed in relation to specific systemic diseases including giant cell arteritis, Takayasu arteritis, granulomatosis with polyangiitis (Wegener's), rheumatoid arthritis, sarcoidosis, ankylosing spondylitis, Cogan syndrome, Behçet's disease, relapsing polychondritis, syphilitic aortitis, and bacterial and fungal infections.

Original languageEnglish (US)
Article number6844
Pages (from-to)267-278
Number of pages12
JournalCardiovascular Pathology
Volume24
Issue number5
DOIs
StatePublished - Sep 1 2015

Keywords

  • Aorta
  • Aortitis
  • Atherosclerosis
  • Inflammatory aneurysm

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases'. Together they form a unique fingerprint.

  • Cite this

    Stone, J. R., Bruneval, P., Angelini, A., Bartoloni, G., Basso, C., Batoroeva, L., Buja, L. M., Butany, J., D'Amati, G., Fallon, J. T., Gittenberger-De Groot, A. C., Gouveia, R. H., Halushka, M. K., Kelly, K. L., Kholova, I., Leone, O., Litovsky, S. H., Maleszewski, J. J., Miller, D. V., ... Veinot, J. P. (2015). Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases. Cardiovascular Pathology, 24(5), 267-278. [6844]. https://doi.org/10.1016/j.carpath.2015.05.001