Congress on women's health trudy bush lecture 2014: New insights into sex hormones and cardiovascular disease

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Many basic, mechanistic studies of how sex steroids alter vascular function proceeded from Dr. Bush's seminal epidemiologic observations that noncontraceptive use of estrogen reduced all-cause and cardiovascular mortality. However, translating findings from these basic science studies into clinical trials and clinical guidelines has been controversial. This commentary reviews the development of sex steroid vascular research, identifies mechanisms by which sex steroids affect vascular function, reviews findings from recent clinical hormone trials, and identifies challenges and the need for continued funding of such investigations.

Original languageEnglish (US)
Pages (from-to)997-1004
Number of pages8
JournalJournal of Women's Health
Volume23
Issue number12
DOIs
StatePublished - Dec 1 2014

ASJC Scopus subject areas

  • Medicine(all)

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