CLE is an emerging technology that has the potential to significantly reduce the number of biopsies in BE and IBD and reduce the need for removal of non-neoplastic colorectal polyps compared with WLE. In the bile duct and within pancreatic cysts, it can provide surrogate real-time histological information that has previously been unavailable. Limitations of CLE include the high cost of the equipment and probes, the lack of proven efficacy compared with other widely available advanced imaging techniques, and the need for either intravenous or topical fluorescent ontrast agents. Before the technology can be widely accepted, many further studies are needed to determine its clinical efficacy and evaluate its cost-effectiveness and its utilization in both academic and community settings.
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging