TY - JOUR
T1 - Conflict of interest
AU - Holmes, David R.
AU - Firth, Brian G.
AU - James, Astrid
AU - Winslow, Ron
AU - Hodgson, Patricia K.
AU - Gamble, Gail L.
AU - Popp, Richard L.
AU - Harrington, Robert A.
N1 - Funding Information:
The meeting upon which this manuscript is based was supported by grants from Cordis Corporation, Boston Scientific, and Merck Research Laboratories. The development of new technology to improve the care of patients is a significant part of academic medical centers' tripartite mission of research, teaching, and patient care. Clinical research activities, with their potential for conflict of interest, have become the subject of intense scrutiny by both the lay and the professional press. Although relatively easy to identify when it has actually affected an outcome, conflict of interest is often more complex when it remains just a potential threat to an outcome. Conflict of interest has many aspects—both financial (direct and/or indirect) and nonfinancial, as well as individual, organizational, and societal. Multiple constituencies are involved in conflict of interest issues and they are often intertwined.
PY - 2004/2
Y1 - 2004/2
N2 - The clinical research enterprise is increasingly scrutinized, in part because of the issue of conflict of interest. The issue is broad and its implications touch on a wide range of concerns, from the safety of patient care to the viability of a large industry. Numerous constituencies are affected by conflict of interest, and representatives of all of them convened in November 2002 for a one-and-a-half day discussion of the issues as well as possible solutions to both the perception and the actuality of such conflict. Participants included medical journal editors, news reporters, physician investigators, representatives of institutional conflict-of-interest oversight committees, representatives of the medical products industry, and Federal regulators. The resulting manuscript provides a review of the issues as well as desirable ways for each of the players to monitor themselves; each section thus contains provocative recommendations for eliminating conflict of interest to ensure that our vibrant health care system continues to foster exciting new advances to improve patient care.
AB - The clinical research enterprise is increasingly scrutinized, in part because of the issue of conflict of interest. The issue is broad and its implications touch on a wide range of concerns, from the safety of patient care to the viability of a large industry. Numerous constituencies are affected by conflict of interest, and representatives of all of them convened in November 2002 for a one-and-a-half day discussion of the issues as well as possible solutions to both the perception and the actuality of such conflict. Participants included medical journal editors, news reporters, physician investigators, representatives of institutional conflict-of-interest oversight committees, representatives of the medical products industry, and Federal regulators. The resulting manuscript provides a review of the issues as well as desirable ways for each of the players to monitor themselves; each section thus contains provocative recommendations for eliminating conflict of interest to ensure that our vibrant health care system continues to foster exciting new advances to improve patient care.
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U2 - 10.1016/j.ahj.2003.12.001
DO - 10.1016/j.ahj.2003.12.001
M3 - Article
C2 - 14760318
AN - SCOPUS:0842282731
SN - 0002-8703
VL - 147
SP - 228
EP - 237
JO - American heart journal
JF - American heart journal
IS - 2
ER -