Conducting systematic reviews of diagnostic studies: Didactic guidelines

Walter L. Devillé, Frank Buntinx, Lex M. Bouter, Victor M. Montori, Henrica C.W. De Vet, Danielle A.W.M. Van Der Windt, P. Dick Bezemer

Research output: Contribution to journalReview article

674 Scopus citations

Abstract

Background: Although guidelines for critical appraisal of diagnostic research and meta-analyses have already been published, these may be difficult to understand for clinical researchers or do not provide enough detailed information. Methods: Development of guidelines based on a systematic review of the evidence in reports of systematic searches of the literature for diagnostic research, of methodological criteria to evaluate diagnostic research, of methods for statistical pooling of data on diagnostic accuracy, and of methods for exploring heterogeneity. Results: Guidelines for conducting diagnostic systematic reviews are presented in a stepwise fashion and are followed by comments providing further information. Examples are given using the results of two systematic reviews on the accuracy of the urine dipstick in the diagnosis of urinary tract infections, and on the accuracy of the straight-leg-raising test in the diagnosis of intervertebral disc hernia.

Original languageEnglish (US)
Article number9
Pages (from-to)1-13
Number of pages13
JournalBMC Medical Research Methodology
Volume2
DOIs
StatePublished - Jul 3 2002

ASJC Scopus subject areas

  • Epidemiology
  • Health Informatics

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    Devillé, W. L., Buntinx, F., Bouter, L. M., Montori, V. M., De Vet, H. C. W., Van Der Windt, D. A. W. M., & Bezemer, P. D. (2002). Conducting systematic reviews of diagnostic studies: Didactic guidelines. BMC Medical Research Methodology, 2, 1-13. [9]. https://doi.org/10.1186/1471-2288-2-9