Concurrent takayasu arteritis with common variable immunodeficiency and moyamoya disease

Nedaa Skeik, Kyle K. Rumery, Prabhu D. Udayakumar, Benjamin M. Crandall, Kenneth J. Warrington, Timothy M. Sullivan

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Takayasu arteritis is a rare, chronic form of large vessel vasculitis that characteristically involves the aorta and its branches. Its origin and disease process are currently unknown, although T lymphocytes and, most recently, B cells are thought to play a role. Common variable immunodeficiency (CVID) is a collection of heterogeneous disorders resulting in an antibody deficiency and recurrent infections, and is the most common symptomatic primary immunodeficiency disorder. This report presents a unique case of possible Takayasu arteritis with a history of CVID in a young man admitted with multiple cerebrovascular accidents. Takayasu arteritis may serve as the main cause of this presentation. The rarity of this case is further accentuated by the presence of moyamoya disease. Finally, the possible disease process and novel treatment of Takayasu arteritis is discussed briefly.

Original languageEnglish (US)
Pages (from-to)240.e13-240.e18
JournalAnnals of Vascular Surgery
Volume27
Issue number2
DOIs
StatePublished - Feb 2013

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

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