Concealed long QT syndrome and intractable partial epilepsy: A case report

Jason H. Anderson, Johan Martijn Bos, Fredric B. Meyer, Gregory D. Cascino, Michael J. Ackerman

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Herein, we describe a patient with concealed type 2 long QT syndrome with concomitant electroencephalogramdocumented epilepsy. Although syncope in patients with long QT syndrome is common and often secondary to cerebral hypoxia after a protracted ventricular arrhythmia, this article demonstrates the importance of avoiding "tunnel vision" as patients with long QT syndrome could also have a primary seizure disorder. Identification of the etiology underlying seizurelike activity is paramount in instituting effective therapy. Furthermore, we theorize that abnormal KCHN2- encoded potassium channel repolarization in the brain could result in epilepsy and arrhythmias in long QT syndrome.

Original languageEnglish (US)
Pages (from-to)1128-1131
Number of pages4
JournalMayo Clinic proceedings
Volume87
Issue number11
DOIs
StatePublished - Nov 2012

ASJC Scopus subject areas

  • General Medicine

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