Computerized Tomography and Adrenoleukomyeloneuropathy: Differential Appearance in Disease Subtypes

Brian P. O'Neill; Glenn S. Forbes

doi:10.1001/archneur.1981.00510050059009

Computerized Tomography and Adrenoleukomyeloneuropathy: Differential Appearance in Disease Subtypes

Brian P. O'Neill, Glenn S. Forbes

Neurology

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Five cases of adrenoleukomyeloneuropathy illustrate the differential computerized tomographic (CT) appearance of the disease subtypes adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN). In ALD, the CT is distinctive, reflecting predominant involvement of cerebral white matter. The CT in AMN may be nonspecifically abnormal since the spinal and peripheral white matter are mainly affected. Recognition of an obscure neurologic disease as a leukodystrophy may aid the clinician in designing appropriate biochemical testing and in categorizing the disease process.

Original language	English (US)
Pages (from-to)	293-296
Number of pages	4
Journal	Archives of neurology
Volume	38
Issue number	5
DOIs	https://doi.org/10.1001/archneur.1981.00510050059009
State	Published - May 1981

ASJC Scopus subject areas

Arts and Humanities (miscellaneous)
Clinical Neurology

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abstract = "Five cases of adrenoleukomyeloneuropathy illustrate the differential computerized tomographic (CT) appearance of the disease subtypes adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN). In ALD, the CT is distinctive, reflecting predominant involvement of cerebral white matter. The CT in AMN may be nonspecifically abnormal since the spinal and peripheral white matter are mainly affected. Recognition of an obscure neurologic disease as a leukodystrophy may aid the clinician in designing appropriate biochemical testing and in categorizing the disease process.",

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AB - Five cases of adrenoleukomyeloneuropathy illustrate the differential computerized tomographic (CT) appearance of the disease subtypes adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN). In ALD, the CT is distinctive, reflecting predominant involvement of cerebral white matter. The CT in AMN may be nonspecifically abnormal since the spinal and peripheral white matter are mainly affected. Recognition of an obscure neurologic disease as a leukodystrophy may aid the clinician in designing appropriate biochemical testing and in categorizing the disease process.

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Computerized Tomography and Adrenoleukomyeloneuropathy: Differential Appearance in Disease Subtypes

Abstract

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