Computer-aided polyp detection for laxative-free CT colonography

Neil Panjwani, Marius George Linguraru, Joel G. Fletcher, Ronald M. Summers

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

Image-based colon cleansing performed on fecal-tagged CT colonography (CTC) allows the laxative-free detection of colon polyps, unlike optical colonoscopy (OC), the preferred screening method. Compared to OC, CTC increases the patient comfort and compliance with colon cancer screening. However, laxative-free CTC introduces many challenges and imaging artifacts, such as poorly and heterogeneously tagged stool, thin stool close to the colon walls, pseudoenhancement of colon tissue, and partial volume effect. We propose an automated algorithm to subtract stool prior to the computer aided detection of colonic polyps. The method is locally adaptive and combines intensity, shape and texture analysis with probabilistic optimization. Results show stool removal accuracy on data with various bowel preparations. The automatic detection of polyps using our CAD system on cathartic-free data improves significantly from 70% to 85% true positive rate at 5.75 false positives/scan.

Original languageEnglish (US)
Title of host publicationAbdominal Imaging
Subtitle of host publicationComputational and Clinical Applications - Third International Workshop, Held in Conjunction with MICCAI 2011, Revised Selected Papers
Pages18-26
Number of pages9
DOIs
StatePublished - Mar 21 2012
Event3rd International Workshop on Computational and Clinical Applications in Abdominal Imaging, Held in Conjunction with the 14th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2011 - Toronto, ON, Canada
Duration: Sep 18 2011Sep 18 2011

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume7029 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other3rd International Workshop on Computational and Clinical Applications in Abdominal Imaging, Held in Conjunction with the 14th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2011
CountryCanada
CityToronto, ON
Period9/18/119/18/11

Keywords

  • CTC
  • cleansing
  • colon cancer
  • heterogeneous stool
  • laxative-free
  • polyp detection

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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