Computed tomography for diagnosis of hepatic rupture in primary systemic amyloidosis

Dennis A. Gastineau, Morie A. Gertz, Charles B. Rosen, Robert A. Kyle

Research output: Contribution to journalArticle

23 Scopus citations


Hepatic rupture in primary systemic amyloidosis is extremely ominous; death occurs in hours to days. We present two cases of hepatic rupture diagnosed ante mortem with computed tomography (CT). Surgical repair was possible in one instance and successfully controlled the bleeding. In the setting of primary amyloidosis, the early use of CT scanning for undiagnosed ascites, hypotension, or rapid organ enlargement may lead to early diagnosis and potential surgical correction.

Original languageEnglish (US)
Pages (from-to)194-196
Number of pages3
JournalAmerican journal of hematology
Issue number3
StatePublished - Jul 1991



  • amyloidosis
  • ante mortem
  • bleeding
  • hepatic rupture
  • surgical repair

ASJC Scopus subject areas

  • Hematology

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