Computed tomographic scan correlates of auditory comprehension deficits in aphasia: A prospective recovery study

O. A. Selnes, David S Knopman, N. Niccum, A. B. Rubens, D. Larson

Research output: Contribution to journalArticle

96 Citations (Scopus)

Abstract

Lesion localization and volume as assessed on computed tomography were analyzed to determine their relationships to auditory comprehension deficits following left hemisphere ischemic stroke in 39 patients. Auditory comprehension was initially tested approximately four weeks after onset, and then monthly for five months, using the Token Test, a series of commands of increasing complexity. Computed tomographic scans obtained five months after onset were used for lesion localization and volume determination. Lesions in the posterior superior temporal and infrasylvian supramarginal regions were strongly associated with poor outcome. Patients with initially preserved auditory comprehension tended to have lesions that spared these regions, whereas patients with persistent deficits had lesions that included these regions. Six of 8 patients who initially had severe deficits in auditory comprehension but recovered completely lacked lesions in these regions. Lesion volume except when very large or very small was not closely associated with outcome.

Original languageEnglish (US)
Pages (from-to)558-566
Number of pages9
JournalAnnals of Neurology
Volume13
Issue number5
StatePublished - 1983
Externally publishedYes

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Aphasia
Prospective Studies
Stroke
Tomography

ASJC Scopus subject areas

  • Neuroscience(all)

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Computed tomographic scan correlates of auditory comprehension deficits in aphasia : A prospective recovery study. / Selnes, O. A.; Knopman, David S; Niccum, N.; Rubens, A. B.; Larson, D.

In: Annals of Neurology, Vol. 13, No. 5, 1983, p. 558-566.

Research output: Contribution to journalArticle

Selnes, O. A. ; Knopman, David S ; Niccum, N. ; Rubens, A. B. ; Larson, D. / Computed tomographic scan correlates of auditory comprehension deficits in aphasia : A prospective recovery study. In: Annals of Neurology. 1983 ; Vol. 13, No. 5. pp. 558-566.
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