Comprehensively understanding fatigue in patients with myeloproliferative neoplasms

Robyn M. Scherber, Heidi E. Kosiorek, Zhenya Senyak, Amylou Dueck, Matthew M Clark, Michael A. Boxer, Holly L. Geyer, Archie Mccallister, Mary Cotter, Barbara Van Husen, Claire N. Harrison, Ruben A. Mesa

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

BACKGROUND: Patients with myeloproliferative neoplasms (MPNs) experience a high persistence, prevalence, and severity of fatigue. There is currently only limited information regarding factors that contribute to fatigue in patients with MPNs. METHODS: A 70-item, Internet-based survey regarding fatigue was developed by MPN investigators and patients/advocates and hosted by the Mayo Clinic Survey Research Center. RESULTS: Fatigue was found to be prevalent and severe among international survey respondents (1788 respondents). Higher body mass index (P2 on the Patient Health Questionnaire, indicating a high probability of depression. Higher Brief Fatigue Inventory score, Myeloproliferative Neoplasm Total Symptom Score, and individual symptom items were all associated with a higher likelihood of depressive symptoms (P

Original languageEnglish (US)
JournalCancer
DOIs
StateAccepted/In press - 2015

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Keywords

  • Essential thrombocythemia
  • Fatigue
  • Myelofibrosis
  • Polycythemia vera
  • Quality of life

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Scherber, R. M., Kosiorek, H. E., Senyak, Z., Dueck, A., Clark, M. M., Boxer, M. A., Geyer, H. L., Mccallister, A., Cotter, M., Van Husen, B., Harrison, C. N., & Mesa, R. A. (Accepted/In press). Comprehensively understanding fatigue in patients with myeloproliferative neoplasms. Cancer. https://doi.org/10.1002/cncr.29753