TY - JOUR
T1 - Comprehensive Identification of Somatic Mutations in Chronic Lymphocytic Leukemia
AU - Bergsagel, P. Leif
AU - Kuehl, W. Michael
PY - 2011/7/12
Y1 - 2011/7/12
N2 - Massively parallel sequencing enables the sequencing of whole genomes, exomes, and transcriptomes from many tumor samples. Thus, it now is possible to comprehensively identify somatic mutations, including single base changes, deletions, insertions, and genomic rearrangements. Early results for hematopoietic tumors show great promise, but many questions remain to be answered.
AB - Massively parallel sequencing enables the sequencing of whole genomes, exomes, and transcriptomes from many tumor samples. Thus, it now is possible to comprehensively identify somatic mutations, including single base changes, deletions, insertions, and genomic rearrangements. Early results for hematopoietic tumors show great promise, but many questions remain to be answered.
UR - http://www.scopus.com/inward/record.url?scp=79960049427&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79960049427&partnerID=8YFLogxK
U2 - 10.1016/j.ccr.2011.06.023
DO - 10.1016/j.ccr.2011.06.023
M3 - Short survey
C2 - 21741593
AN - SCOPUS:79960049427
SN - 1535-6108
VL - 20
SP - 5
EP - 7
JO - Cancer cell
JF - Cancer cell
IS - 1
ER -