Comprehensive assessment of childhood attention-deficit hyperactivity disorder in the context of a multisite, multimodal clinical trial

S. P. Hinshaw, J. S. March, H. Abikoff, L. E. Arnold, D. P. Cantwell, C. K. Conners, G. R. Elliott, J. Halperin, L. L. Greenhill, L. T. Hechtman, B. Hoza, P. S. Jensen, J. H. Newcorn, K. McBurnett, W. E. Pelham, J. E. Richters, J. B. Severe, E. Schiller, J. Swanson, D. VereenK. Wells, T. Wigal

Research output: Contribution to journalArticle

133 Citations (Scopus)

Abstract

As the largest randomized clinical trial conducted by the National Institute of Mental Health, the Multimodal Treatment Study of Children with ADHD (MTA) will yield data on a diverse sample of 576 7.0- to 9.9-year-old children with attention-deficit hyperactivity disorder (ADHD), Combined type, regarding the relative and combined effectiveness of psychosocial and pharmacologic interventions. After delineating key challenges posed by such a multisite investigation, we describe the MTA's multiple-gating procedures for recruitment, screening, and diagnosis of a diverse sample. We then discuss the cross-domain assessment battery for tracking the sample before, during, and after 14 months of active intervention. Throughout, we emphasize the guiding principles that shaped pertinent decision making. Highlighted are issues of psychometric adequacy; dimensional vs. categorical measurement; multi-method, multi-agent, and multi-domain coverage; plotting of individual trajectories of development and change; respondent bias and burden; appraisal of treatment processes as well as outcomes; and construction of composite indices.

Original languageEnglish (US)
Pages (from-to)217-234
Number of pages18
JournalJournal of Attention Disorders
Volume1
Issue number4
StatePublished - Jan 1997
Externally publishedYes

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Pemetrexed
Attention Deficit Disorder with Hyperactivity
Clinical Trials
National Institute of Mental Health (U.S.)
Combined Modality Therapy
Psychometrics
Decision Making
Randomized Controlled Trials
Therapeutics

ASJC Scopus subject areas

  • Psychology(all)

Cite this

Hinshaw, S. P., March, J. S., Abikoff, H., Arnold, L. E., Cantwell, D. P., Conners, C. K., ... Wigal, T. (1997). Comprehensive assessment of childhood attention-deficit hyperactivity disorder in the context of a multisite, multimodal clinical trial. Journal of Attention Disorders, 1(4), 217-234.

Comprehensive assessment of childhood attention-deficit hyperactivity disorder in the context of a multisite, multimodal clinical trial. / Hinshaw, S. P.; March, J. S.; Abikoff, H.; Arnold, L. E.; Cantwell, D. P.; Conners, C. K.; Elliott, G. R.; Halperin, J.; Greenhill, L. L.; Hechtman, L. T.; Hoza, B.; Jensen, P. S.; Newcorn, J. H.; McBurnett, K.; Pelham, W. E.; Richters, J. E.; Severe, J. B.; Schiller, E.; Swanson, J.; Vereen, D.; Wells, K.; Wigal, T.

In: Journal of Attention Disorders, Vol. 1, No. 4, 01.1997, p. 217-234.

Research output: Contribution to journalArticle

Hinshaw, SP, March, JS, Abikoff, H, Arnold, LE, Cantwell, DP, Conners, CK, Elliott, GR, Halperin, J, Greenhill, LL, Hechtman, LT, Hoza, B, Jensen, PS, Newcorn, JH, McBurnett, K, Pelham, WE, Richters, JE, Severe, JB, Schiller, E, Swanson, J, Vereen, D, Wells, K & Wigal, T 1997, 'Comprehensive assessment of childhood attention-deficit hyperactivity disorder in the context of a multisite, multimodal clinical trial', Journal of Attention Disorders, vol. 1, no. 4, pp. 217-234.
Hinshaw, S. P. ; March, J. S. ; Abikoff, H. ; Arnold, L. E. ; Cantwell, D. P. ; Conners, C. K. ; Elliott, G. R. ; Halperin, J. ; Greenhill, L. L. ; Hechtman, L. T. ; Hoza, B. ; Jensen, P. S. ; Newcorn, J. H. ; McBurnett, K. ; Pelham, W. E. ; Richters, J. E. ; Severe, J. B. ; Schiller, E. ; Swanson, J. ; Vereen, D. ; Wells, K. ; Wigal, T. / Comprehensive assessment of childhood attention-deficit hyperactivity disorder in the context of a multisite, multimodal clinical trial. In: Journal of Attention Disorders. 1997 ; Vol. 1, No. 4. pp. 217-234.
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