Compositional analysis of the human microbiome in cancer research

Elisa Morales, Jun Chen, K. Leigh Greathouse

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Gut microbial composition has shown to be associated with obesity, diabetes mellitus, inflammatory bowel disease, colitis, autoimmune disorders, and cancer, among other diseases. Microbiome research has significantly evolved through the years and continues to advance as we develop new and better strategies to more accurately measure its composition and function. Careful selection of study design, inclusion and exclusion criteria of participants, and methodology are paramount to accurately analyze microbial structure. Here we present the most up-to-date available information on methods for gut microbial collection and analysis.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages299-335
Number of pages37
DOIs
StatePublished - Jan 1 2019

Publication series

NameMethods in Molecular Biology
Volume1928
ISSN (Print)1064-3745

Keywords

  • Cancer research
  • Gut microbiota
  • Metagenomic sequencing
  • Taxonomic classification

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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  • Cite this

    Morales, E., Chen, J., & Greathouse, K. L. (2019). Compositional analysis of the human microbiome in cancer research. In Methods in Molecular Biology (pp. 299-335). (Methods in Molecular Biology; Vol. 1928). Humana Press Inc.. https://doi.org/10.1007/978-1-4939-9027-6_16