Complications and risk factors after ileal pouch-anal anastomosis for ulcerative colitis associated with primary sclerosing cholangitis

A. H. Kartheuser, R. R. Dozois, R. H. Wiesner, Nicholas F La Russo, D. M. Ilstrup, C. D. Schleck

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Objective. This study determined predictive factors for postoperative complications and outcome after ileal pouch-anal anastomosis in patients with ulcerative colitis and primary sclerosing cholangitis. Summary Background Data. Patients with ulcerative colitis and primary sclerosing cholangitis treated by colectomy and ileostomy are at high risk of troublesome bleeding from peristomal varices. Methods. Postoperative complications and outcome were assessed in 40 patients with ulcerative colitis and sclerosing cholangitis who received an ileal pouch-anal anastomosis between January 1981 and February 1990. Results. Immediate postoperative and remote ileoanal anastomosis-related complications were high but related directly to the severity of liver disease. No patient had perianastomotic anal bleeding. Conclusions. In patients with both ulcerative colitis and primary sclerosing cholangitis, ileal pouch-anal anastomosis is safe and is not associated with perianastomotic bleeding.

Original languageEnglish (US)
Pages (from-to)314-320
Number of pages7
JournalAnnals of Surgery
Volume217
Issue number4
StatePublished - 1993

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Colonic Pouches
Sclerosing Cholangitis
Ulcerative Colitis
Hemorrhage
Ileostomy
Colectomy
Varicose Veins
Liver Diseases

ASJC Scopus subject areas

  • Surgery

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Complications and risk factors after ileal pouch-anal anastomosis for ulcerative colitis associated with primary sclerosing cholangitis. / Kartheuser, A. H.; Dozois, R. R.; Wiesner, R. H.; La Russo, Nicholas F; Ilstrup, D. M.; Schleck, C. D.

In: Annals of Surgery, Vol. 217, No. 4, 1993, p. 314-320.

Research output: Contribution to journalArticle

Kartheuser, A. H. ; Dozois, R. R. ; Wiesner, R. H. ; La Russo, Nicholas F ; Ilstrup, D. M. ; Schleck, C. D. / Complications and risk factors after ileal pouch-anal anastomosis for ulcerative colitis associated with primary sclerosing cholangitis. In: Annals of Surgery. 1993 ; Vol. 217, No. 4. pp. 314-320.
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AU - Kartheuser, A. H.

AU - Dozois, R. R.

AU - Wiesner, R. H.

AU - La Russo, Nicholas F

AU - Ilstrup, D. M.

AU - Schleck, C. D.

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AB - Objective. This study determined predictive factors for postoperative complications and outcome after ileal pouch-anal anastomosis in patients with ulcerative colitis and primary sclerosing cholangitis. Summary Background Data. Patients with ulcerative colitis and primary sclerosing cholangitis treated by colectomy and ileostomy are at high risk of troublesome bleeding from peristomal varices. Methods. Postoperative complications and outcome were assessed in 40 patients with ulcerative colitis and sclerosing cholangitis who received an ileal pouch-anal anastomosis between January 1981 and February 1990. Results. Immediate postoperative and remote ileoanal anastomosis-related complications were high but related directly to the severity of liver disease. No patient had perianastomotic anal bleeding. Conclusions. In patients with both ulcerative colitis and primary sclerosing cholangitis, ileal pouch-anal anastomosis is safe and is not associated with perianastomotic bleeding.

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