Complications and risk factors after heal pouch-anal anastomosis for ulcerative colitis associated with primary sclerosing cholangitis

Alex H. Kartheuser, Roger R. Dozois, Russell H. Wiesner, Nicholas F. LaRusso, Duane M. Ilstrup, Cathy D. Schleck

Research output: Contribution to journalArticlepeer-review

51 Scopus citations

Abstract

Objective: This study determined predictive factors for postoperative complications and outcome after ileal pouch-anal anastomosis in patients with ulcerative colitis and primary sclerosing cholangitis. Summary Background Data: Patients with ulcerative colitis and primary sclerosing cholangitis treated by colectomy and ileostomy are at high risk of troublesome bleeding from peristomal varices. Methods: Postoperative complications and outcome were assessed in 40 patients with ulcerative colitis and sclerosing cholangitis who received an ileal pouch-anal anastomosis between January 1981 and February 1990. Results: Immediate postoperative and remote ileoanal anastomosis-related complications were high but related directly to the severity of liver disease. No patient had perianastomotic anal bleeding. Conclusions: In patients with both ulcerative colitis and primary sclerosing cholangitis, ieal pouch-anal anastomosis is safe and is not associated with perianastomotic bleeding.

Original languageEnglish (US)
Pages (from-to)314-320
Number of pages7
JournalAnnals of surgery
Volume217
Issue number4
DOIs
StatePublished - Apr 1993

ASJC Scopus subject areas

  • Surgery

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