Complications and outcomes of SARS-CoV-2 in pregnancy: where and what is the evidence?

Ayssa Teles Abrao Trad, Eniola R. Ibirogba, Amro Elrefaei, Kavita Narang, Gabriele Tonni, Olivier Picone, Anna Suy, Elena Carreras Moratonas, Mark D. Kilby, Rodrigo Ruano

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Objectives: To add to the growing evidence on SARS-CoV-2 infection during pregnancy, so as to better inform clinical decision making and optimize patient outcomes. Methods: A systematic search of relevant databases was perfomed on 25 March 2020 and a repeat search, on 10 April 2020. Reports of pregnant patients with SARS-CoV-2 infection at any time during their pregnancy were reviewed and summarized. Results: We summarized the outcomes of a total of 155 pregnant women and 118 neonates. The evidence suggests a similar rate of severe COVID-19 cases in pregnant women and the general population. The frequency of cesarean deliveries is high, against guidelines recommendations. Conclusion: Limited data on COVID-19 during preganacy, associated with a wide variation in the methodology make accurate data interpretation difficult.

Original languageEnglish (US)
Pages (from-to)361-369
Number of pages9
JournalHypertension in Pregnancy
Issue number3
StatePublished - Jul 2 2020


  • SARS-CoV-2
  • perinatal
  • pregnancy
  • vertical transmission

ASJC Scopus subject areas

  • Internal Medicine
  • Obstetrics and Gynecology


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