Complex vascular lesions at autopsy in a patient with phentermine- fenfluramine use and rapidly progressing pulmonary hypertension

Jennifer Strother, Peter Fedullo, Eunhee S. Yi, Eliezer Masliah

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Anorectic agents, such as aminorex and fenfluramine derivatives, have been associated previously with the development of primary pulmonary hypertension. The combination diet drug phentermine-fenfluramine (or 'phen- fen') was recently marketed in the United States. We describe a case of a 39- year-old woman with rapidly progressing, fatal pulmonary hypertension following administration of phentermine-fenfluramine. Autopsy was remarkable for complex pulmonary vascular lesions most consistent with thrombotic arteriopathy.

Original languageEnglish (US)
Pages (from-to)539-540
Number of pages2
JournalArchives of Pathology and Laboratory Medicine
Volume123
Issue number6
StatePublished - Jun 10 1999

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ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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