Complete response in Patients With Lung-Only Metastatic Prostate Cancer: Outcome Analysis

Adam M. Kase, John A. Copland, Qihui Zhai, Winston Tan

Research output: Contribution to journalArticlepeer-review

Abstract

Lung-only metastatic prostate cancer can be seen in 4.6% of patients and historically patients with visceral metastastic disease are considered high risk. In order to determine survival outcomes in this patient population, we conducted a restrospective review of patients with metastatic hormone sensitive prostate cancer with lung-only metastases. In this single institution review, 10 patients were identified with 8 achieving a complete response and 2 achieving a partial response when treated with androgen deprevation therapy (ADT) with or without metastastetomy. The median progression free survival was 64.4 months with 8 of these patients (80%) with ongoing complete response at time of follow-up. Lung-only metastases may serve as a good prognostic characteristic which will allow the clinician to treat with ADT alone with or without surgery to minimize treatment realted toxicity and still offer the ability to achieve a complete response with prolonged survival.

Original languageEnglish (US)
JournalClinical Genitourinary Cancer
DOIs
StateAccepted/In press - 2022

Keywords

  • Androgen deprivation therapy (ADT)
  • Complete response
  • Lung metastases
  • Lung-only metastatic prostate cancer
  • Metastatic hormone sensitive prostate cancer
  • Oligometastatic prostate cancer

ASJC Scopus subject areas

  • Oncology
  • Urology

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